IED ID | IndEnz0002001813 |
Enzyme Type ID | protease001813 |
Protein Name |
Serine protease SplB EC 3.4.21.- |
Gene Name | splB |
Organism | Staphylococcus aureus |
Taxonomic Lineage | cellular organisms Bacteria Terrabacteria group Firmicutes Bacilli Bacillales Staphylococcaceae Staphylococcus Staphylococcus aureus |
Enzyme Sequence | MNKNVVIKSLATLTILTSVTGIGTTLVEEVQQTAKAENNVTKIQDTNIFPYTGVVAFKSATGFVVGKNTILTNKHVSKNYKVGDRITAHPNSDKGNGGIYSIKKIINYPGKEDVSVIQVEERAIERGPKGFNFNDNVTPFKYAAGAKAGERIKVIGYPHPYKNKYVLYESTGPVMSVEGSSIVYSAHTESGNSGSPVLNSNNELVGIHFASDVKNDDNRNAYGVYFTPEIKKFIAENIDK |
Enzyme Length | 240 |
Uniprot Accession Number | Q53781 |
Absorption | |
Active Site | ACT_SITE 75; /note=Charge relay system; /evidence=ECO:0000250|UniProtKB:Q2FXC3; ACT_SITE 113; /note=Charge relay system; /evidence=ECO:0000250|UniProtKB:Q2FXC3; ACT_SITE 193; /note=Charge relay system; /evidence=ECO:0000250|UniProtKB:Q2FXC3 |
Activity Regulation | |
Binding Site | |
Calcium Binding | |
catalytic Activity | |
DNA Binding | |
EC Number | 3.4.21.- |
Enzyme Function | FUNCTION: Serine protease that cleaves specifically after the sequence Trp-Glu-Leu-Gln. {ECO:0000250}. |
Temperature Dependency | |
PH Dependency | |
Pathway | |
nucleotide Binding | |
Features | Active site (3); Chain (1); Signal peptide (1) |
Keywords | Hydrolase;Protease;Secreted;Serine protease;Signal |
Interact With | |
Induction | |
Subcellular Location | SUBCELLULAR LOCATION: Secreted {ECO:0000250}. |
Modified Residue | |
Post Translational Modification | |
Signal Peptide | SIGNAL 1..36; /evidence=ECO:0000250 |
Structure 3D | |
Cross Reference PDB | - |
Mapped Pubmed ID | - |
Motif | |
Gene Encoded By | |
Mass | 26,141 |
Kinetics | |
Metal Binding | |
Rhea ID | |
Cross Reference Brenda |