Detail Information for IndEnz0002001824
IED ID IndEnz0002001824
Enzyme Type ID protease001824
Protein Name Extracellular metalloproteinase 1
EC 3.4.24.-
Elastinolytic metalloproteinase MEP1
Fungalysin MEP1
Gene Name MEP1 SNOG_10695
Organism Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) (Glume blotch fungus) (Parastagonospora nodorum)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta dothideomyceta Dothideomycetes Pleosporomycetidae Pleosporales Pleosporineae Phaeosphaeriaceae Parastagonospora Phaeosphaeria nodorum (Glume blotch fungus) (Parastagonospora nodorum) Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) (Glume blotch fungus) (Parastagonospora nodorum)
Enzyme Sequence MLSSLLAGAGLVALAASHPTSHGNALTRRAVDINAFRLTATSEYVNATVAVSEPSLRFLKRADYLETATELVKSVAKDATFRVVEDHYVGSNGIAHVNFKQTANGLDIDNADFNINVAKDGSIFSYGNSFYTGAIPANPLQKRDFSDPVDALKAANDKLQLAVTAEKASAESTGAKETFTLKGTSGAVKDPEAKLVYLVKSDGNLALTWRVETDIMSNWLLTYVDAATNQEIHGVVDYSADATYQVYPWGLNDPTEGSRAVVTNPWDTTASEFTWQGTGTTTYNVPRGNNAIAQSNTDGGSDYLSNYRPTSTSQNFSYPYTLQMSPPSTYVDASVTQLFYTANVYHDLLHSLGFNERAGNFEVNNNGAGGSGNDMVILNTHDGSDTNNANFATPPDGQPGRMRMFLWDLSTPNRDSSFEAGVVIHEYTHGLSNRLTGGPANSNCLNALESGGMGEGWGDFMATAIRLKAGDTRAKDYTMGSWIANDPKGIRTYPYSTSLTTNPHKYTDVNNLRGVHPIGTVWATMLYEVMWNLIDRYGKNDGAKPTFGANGAPTDGKYLAMKLVVDGMALPNFVQARDAILDADVALTGGANKCDIWKGFAKRGLGSGARYSSTARTGSTALPSGC
Enzyme Length 626
Uniprot Accession Number Q0UC19
Absorption
Active Site ACT_SITE 426; /evidence=ECO:0000255|PROSITE-ProRule:PRU10095
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number 3.4.24.-
Enzyme Function FUNCTION: Secreted metalloproteinase that allows assimilation of proteinaceous substrates. {ECO:0000250}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (1); Chain (1); Compositional bias (1); Glycosylation (1); Metal binding (2); Propeptide (1); Region (1); Signal peptide (1)
Keywords Glycoprotein;Hydrolase;Metal-binding;Metalloprotease;Protease;Reference proteome;Secreted;Signal;Zinc;Zymogen
Interact With
Induction INDUCTION: Expression is controlled by the prtT transcription factor.
Subcellular Location SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
Modified Residue
Post Translational Modification
Signal Peptide SIGNAL 1..17; /evidence=ECO:0000255
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 67,217
Kinetics
Metal Binding METAL 425; /note=Zinc; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU10095; METAL 429; /note=Zinc; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU10095
Rhea ID
Cross Reference Brenda