| IED ID | IndEnz0002001829 |
| Enzyme Type ID | protease001829 |
| Protein Name |
Mitochondrial-processing peptidase subunit alpha Alpha-MPP Inactive zinc metalloprotease mppa-1 |
| Gene Name | mppa-1 Y71G12B.24 |
| Organism | Caenorhabditis elegans |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Protostomia Ecdysozoa Nematoda (roundworms) Chromadorea Rhabditida Rhabditina Rhabditomorpha Rhabditoidea Rhabditidae Peloderinae Caenorhabditis Caenorhabditis elegans |
| Enzyme Sequence | MLLRKSIPYIKICRDISASVRNNKEIAQKLPLSVPLPMENNSKSIEKGCPPMGRNSRVTRLPNGLKVCTEDTYGDFVTVGVAIESGCRYENGFPFGISRIVEKLAYNSSESFSSRDEVFAKLEENSGIVDCQSTRDTMMYAASCHRDGVDSVIHVLSDTIWKPIFDEQSLEQAKLTVSYENQDLPNRIEAIEILLTDWIHQAAFQNNTIGYPKFGNNSMDKIRVSDVYGFLSRAHTPQRMVVGGVGVGHDEFVSIISRHFDLNKSTWTTQPTVLPAKIPEIDESRAQYTGGELRLDTDLTKLTIGKPYPLLSHVVLGLEGCSYKDEDFVAFCVLQSLLGGGGAFSAGGPGKGMYARMYTELMNRHHWIYSAIAHNHSYSDSGVFTVTASSPPENINDALILLVHQILQLQQGVEPTELARARTQLRSHLMMNLEVRPVLFEDMVRQVLGHGDRKQPEEYAEKIEKVTNSDIIRVTERLLASKPSLVGYGDIKKLKDLRSLDQAVAKRDLKYLFN |
| Enzyme Length | 514 |
| Uniprot Accession Number | Q95XN2 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | |
| Enzyme Function | FUNCTION: Substrate recognition and binding subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins. {ECO:0000305|PubMed:16788047}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Alternative sequence (1); Chain (1); Transit peptide (1) |
| Keywords | Alternative splicing;Mitochondrion;Reference proteome;Transit peptide |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Mitochondrion matrix {ECO:0000250|UniProtKB:P20069}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | 10778742; 20439774; 20439776; 21085631; 21177967; 21367940; 22267497; 22286215; 22560298; 23800452; 24884423; 25487147; 26564951; 6593563; |
| Motif | |
| Gene Encoded By | |
| Mass | 57,494 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |