Detail Information for IndEnz0002001829
IED ID IndEnz0002001829
Enzyme Type ID protease001829
Protein Name Mitochondrial-processing peptidase subunit alpha
Alpha-MPP
Inactive zinc metalloprotease mppa-1
Gene Name mppa-1 Y71G12B.24
Organism Caenorhabditis elegans
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Protostomia Ecdysozoa Nematoda (roundworms) Chromadorea Rhabditida Rhabditina Rhabditomorpha Rhabditoidea Rhabditidae Peloderinae Caenorhabditis Caenorhabditis elegans
Enzyme Sequence MLLRKSIPYIKICRDISASVRNNKEIAQKLPLSVPLPMENNSKSIEKGCPPMGRNSRVTRLPNGLKVCTEDTYGDFVTVGVAIESGCRYENGFPFGISRIVEKLAYNSSESFSSRDEVFAKLEENSGIVDCQSTRDTMMYAASCHRDGVDSVIHVLSDTIWKPIFDEQSLEQAKLTVSYENQDLPNRIEAIEILLTDWIHQAAFQNNTIGYPKFGNNSMDKIRVSDVYGFLSRAHTPQRMVVGGVGVGHDEFVSIISRHFDLNKSTWTTQPTVLPAKIPEIDESRAQYTGGELRLDTDLTKLTIGKPYPLLSHVVLGLEGCSYKDEDFVAFCVLQSLLGGGGAFSAGGPGKGMYARMYTELMNRHHWIYSAIAHNHSYSDSGVFTVTASSPPENINDALILLVHQILQLQQGVEPTELARARTQLRSHLMMNLEVRPVLFEDMVRQVLGHGDRKQPEEYAEKIEKVTNSDIIRVTERLLASKPSLVGYGDIKKLKDLRSLDQAVAKRDLKYLFN
Enzyme Length 514
Uniprot Accession Number Q95XN2
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number
Enzyme Function FUNCTION: Substrate recognition and binding subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins. {ECO:0000305|PubMed:16788047}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Alternative sequence (1); Chain (1); Transit peptide (1)
Keywords Alternative splicing;Mitochondrion;Reference proteome;Transit peptide
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Mitochondrion matrix {ECO:0000250|UniProtKB:P20069}.
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID 10778742; 20439774; 20439776; 21085631; 21177967; 21367940; 22267497; 22286215; 22560298; 23800452; 24884423; 25487147; 26564951; 6593563;
Motif
Gene Encoded By
Mass 57,494
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda