| IED ID | IndEnz0002001991 |
| Enzyme Type ID | protease001991 |
| Protein Name |
Collagen alpha-1 XXVIII chain |
| Gene Name | Col28a1 Col28 |
| Organism | Mus musculus (Mouse) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Craniata Vertebrata Gnathostomata (jawed vertebrates) Teleostomi Euteleostomi Sarcopterygii Dipnotetrapodomorpha Tetrapoda Amniota Mammalia Theria Eutheria Boreoeutheria Euarchontoglires Glires (Rodents and rabbits) Rodentia Myomorpha (mice and others) Muroidea Muridae Murinae Mus Mus Mus musculus (Mouse) |
| Enzyme Sequence | MRRRDVAFCLLLLPAFMTQAVYGQRKKGPKPNTLARKNDFQDAICFIDVVFILDSSESSKIVLFDNQKDFVDSLSEKIFQLTPGRSLKYDIKLAALQFSSSVQIDPPLSSWKDLRTFKQRVKSLNLIGQGTFSYYAISNATRLLKREGRKDGVKVALLMTDGIDHPKSPDVQSISEDARILGISFITVGLSTVVNEAKLRLISGDPSNEPVLLLSDPTLVDRIQERLGVLFERKCEHKICECEKGEPGDPGPPGTHGNPGIKGERGPKGNPGDAQKGETGERGPVGIPGYKGDKGERGECGKPGMKGDKGPEGPYGPKGPRGIQGIGGPPGDPGPKGFQGNKGEPGPPGPYGPPGAPGIGQQGVKGERGQEGRMGAPGPIGIGEPGQPGPRGPEGAPGERGLPGEGFPGPKGEKGSEGPIGPQGLQGLSIKGDKGDLGPVGPQGPAGIPGIGSQGEQGIQGPSGPPGPQGPPGQGSPGPKGEVGQMGPTGPRGPMGIGVQGPKGEPGTVGLPGQPGVPGEDGASGKKGEAGLPGTRGPEGMPGKGQPGPKGDEGKKGSKGNQGQRGFPGPEGPKGEPGVMGPFGMPGASIPGPSGPKGDRGGPGMPGLKGEPGLPVRGPKGAQGPRGPVGAPGLKGDGYPGVAGPRGLPGPPGPMGLRGVGDTGAKGEPGVRGPPGPSGPRGIGTQGPKGDTGQKGLPGPPGPPGYGSQGIKGEQGPQGFPGSKGTVGLGLPGQKGEHGDRGDVGRKGEKGETGEPGSPGKQGLQGPKGDLGLTKEEIIKLIIEICGCGPKCKETPLELVFVIDSSESVGPENFQIIQSFVKTLADRVALDLGTARIGIINYSHKVEKVASLKQFSSKDDFKLVVDNMQYLGEGTYTATALQAANDMFKEARPGVKKVALVITDGQTDSRDKKKLADVVKDANDSNVEIFVIGVVKKDDPNFEIFHKEMNLIATDAEHVYQFDDFFTLQDTLKQKLSKKICEDFDSYLIQVFGSPSFQPEFGVSEREVSVSTPKPAKEMSKSFNVSRGQNEETESYVLTEAGILAIPTPPEATNTLEPLLSSREGVETRTPNPNLLQSEKSLYKDPRCEEALKPGECGDYVVRWYYDKQVNSCARFWFSGCNGSGNRFHSEKECRETCIKQ |
| Enzyme Length | 1141 |
| Uniprot Accession Number | Q2UY11 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | |
| Enzyme Function | FUNCTION: May act as a cell-binding protein. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Alternative sequence (2); Chain (1); Compositional bias (2); Disulfide bond (3); Domain (8); Region (1); Signal peptide (1) |
| Keywords | Alternative splicing;Basement membrane;Cell adhesion;Collagen;Disulfide bond;Extracellular matrix;Protease inhibitor;Reference proteome;Repeat;Secreted;Serine protease inhibitor;Signal |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular matrix, basement membrane {ECO:0000269|PubMed:16330543}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..20; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | 18799693; 20830809; 22159717; 28071719; |
| Motif | |
| Gene Encoded By | |
| Mass | 118,749 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |