| IED ID | IndEnz0002002062 |
| Enzyme Type ID | protease002062 |
| Protein Name |
Leucine aminopeptidase 1 EC 3.4.11.- Leucyl aminopeptidase 1 LAP1 |
| Gene Name | lap1 AO090206000073 |
| Organism | Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta Eurotiomycetes Eurotiomycetidae Eurotiales (green and blue molds) Aspergillaceae Aspergillus Aspergillus subgen. Circumdati Aspergillus oryzae (Yellow koji mold) Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold) |
| Enzyme Sequence | MKIRAALALSATASGVLAAVVPQQALLNNPQIHHENEKYLIELAPYQTRWVTEEEKWALKLDGVNFIDITEERNPGFYPTLHQASNVRYPTKMEHVEEVVGLTHRLTKANMERDLEKFTSFHTRYYKSQTGIESATWLYNQVQTVIEQSGAAEHGATVDRFAHSWGQFSIIARIPGKSNKTVVLGAHQDSINLFLPSILAAPGADDDGSGTVTILEALRGLLQSDTVAQGKAPNTIEFHWYSAEEGGMLGSQAIFSQYKQERRDIKAMLQQDMTGYVQGALNAGRKEAVGIMIDYVDRGLTQFLKDVVTAYCNVGYLETKCGYACSDHTSASKYGYPSAMATEAEMENTNKRIHTTDDRIKYLSFDHMLEHAKLTLGFAYELAFASF |
| Enzyme Length | 387 |
| Uniprot Accession Number | Q2PIT3 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.11.- |
| Enzyme Function | FUNCTION: Extracellular aminopeptidase that allows assimilation of proteinaceous substrates. {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Disulfide bond (1); Glycosylation (1); Metal binding (6); Propeptide (1); Signal peptide (1) |
| Keywords | Aminopeptidase;Disulfide bond;Glycoprotein;Hydrolase;Metal-binding;Protease;Reference proteome;Secreted;Signal;Zinc;Zymogen |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Secreted {ECO:0000250}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..18; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 43,148 |
| Kinetics | |
| Metal Binding | METAL 187; /note=Zinc 1; /evidence=ECO:0000250; METAL 206; /note=Zinc 1; /evidence=ECO:0000250; METAL 206; /note=Zinc 2; catalytic; /evidence=ECO:0000250; METAL 245; /note=Zinc 2; catalytic; /evidence=ECO:0000250; METAL 272; /note=Zinc 1; /evidence=ECO:0000250; METAL 354; /note=Zinc 2; catalytic; /evidence=ECO:0000250 |
| Rhea ID | |
| Cross Reference Brenda |