IED ID | IndEnz0002002441 |
Enzyme Type ID | protease002441 |
Protein Name |
Germination protease EC 3.4.24.78 GPR endopeptidase Germination proteinase Spore protease |
Gene Name | gpr BAA_4565 |
Organism | Bacillus anthracis (strain A0248) |
Taxonomic Lineage | cellular organisms Bacteria Terrabacteria group Firmicutes Bacilli Bacillales Bacillaceae Bacillus Bacillus cereus group Bacillus anthracis Bacillus anthracis (strain A0248) |
Enzyme Sequence | MKEPLDLSKYSVRTDLAVEAHQMLQERQEEQQQGIQGVIVKEREEEGIIITKVTIDEVASESMGKKPGNYLTLEVQGIRQQDTELQQKVERIFAKEFSYFLEEVGVTKEASCLIVGLGNWNVTPDALGPIVVENVLVTRHLFQLQPESVEEGFRPVSAIRPGVMGITGIETSDVIYGIIEKTKPDFVIAIDALAARSIERVNSTIQISDTGIHPGSGVGNKRKELSKETLGIPVIAIGVPTVVDAVSITSDTIDFILKHFGREMKEGNKPSRSLLPAGFTFGEKKKLTEEDMPDEKSRNMFLGAVGTLEDEEKRKLIYEVLSPLGHNLMVTPKEVDAFIEDMANVIASGLNAALHHQIDQDNTGAYTH |
Enzyme Length | 368 |
Uniprot Accession Number | C3P8M7 |
Absorption | |
Active Site | |
Activity Regulation | |
Binding Site | |
Calcium Binding | |
catalytic Activity | CATALYTIC ACTIVITY: Reaction=Endopeptidase action with P4 Glu or Asp, P1 preferably Glu > Asp, P1' hydrophobic and P2' Ala.; EC=3.4.24.78; Evidence={ECO:0000255|HAMAP-Rule:MF_00626}; |
DNA Binding | |
EC Number | 3.4.24.78 |
Enzyme Function | FUNCTION: Initiates the rapid degradation of small, acid-soluble proteins during spore germination. {ECO:0000255|HAMAP-Rule:MF_00626}. |
Temperature Dependency | |
PH Dependency | |
Pathway | |
nucleotide Binding | |
Features | Chain (1); Propeptide (1) |
Keywords | Hydrolase;Protease;Zymogen |
Interact With | |
Induction | |
Subcellular Location | |
Modified Residue | |
Post Translational Modification | PTM: Autoproteolytically processed. The inactive tetrameric zymogen termed p46 autoprocesses to a smaller form termed p41, which is active only during spore germination. {ECO:0000255|HAMAP-Rule:MF_00626}. |
Signal Peptide | |
Structure 3D | |
Cross Reference PDB | - |
Mapped Pubmed ID | - |
Motif | |
Gene Encoded By | |
Mass | 40,605 |
Kinetics | |
Metal Binding | |
Rhea ID | |
Cross Reference Brenda |