Detail Information for IndEnz0002002687
IED ID IndEnz0002002687
Enzyme Type ID protease002687
Protein Name Proteinase inhibitor A
Double-headed proteinase inhibitor A
API-A
Gene Name
Organism Sagittaria sagittifolia (Arrowhead)
Taxonomic Lineage cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae Liliopsida Alismatales Alismataceae Sagittaria Sagittaria sagittifolia (Arrowhead)
Enzyme Sequence MAASNALLLISGVLLISLAVLCHGDPVVDSDGDAVQLNLGGNYPLYTIQSAAIGFRGGLSTLHKDACKSYVYEAPETDRGLPVGFSASATSQPVMQLGSRYKFSFSMPVPLICDTAWSIGKSTEETGVYKLAACSCEFCKIACPEVGSFNVNGRTLLGIGGEHFTVRFQKFDALAMKTAPQ
Enzyme Length 181
Uniprot Accession Number P31608
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number
Enzyme Function FUNCTION: Possesses two reactive sites. Inhibits an equimolar amount of trypsin and chymotrypsin simultaneously, and inhibits kallikrein weakly.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Chain (1); Disulfide bond (3); Sequence conflict (5); Signal peptide (1); Site (2)
Keywords Direct protein sequencing;Disulfide bond;Protease inhibitor;Secreted;Serine protease inhibitor;Signal
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Secreted.
Modified Residue
Post Translational Modification
Signal Peptide SIGNAL 1..24; /evidence=ECO:0000269|PubMed:1618743
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 19,152
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda