IED ID | IndEnz0002002689 |
Enzyme Type ID | protease002689 |
Protein Name |
Trypsin inhibitor 2 EETI-II Trypsin inhibitor II |
Gene Name | |
Organism | Ecballium elaterium (Squirting cucumber) (Momordica elaterium) |
Taxonomic Lineage | cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae eudicotyledons Gunneridae Pentapetalae rosids fabids Cucurbitales Cucurbitaceae Bryonieae Ecballium Ecballium elaterium (Squirting cucumber) (Momordica elaterium) |
Enzyme Sequence | GCPRILMRCKQDSDCLAGCVCGPNGFCGSP |
Enzyme Length | 30 |
Uniprot Accession Number | P12071 |
Absorption | |
Active Site | |
Activity Regulation | |
Binding Site | |
Calcium Binding | |
catalytic Activity | |
DNA Binding | |
EC Number | |
Enzyme Function | FUNCTION: Inhibits trypsin. |
Temperature Dependency | |
PH Dependency | |
Pathway | |
nucleotide Binding | |
Features | Beta strand (2); Disulfide bond (3); Helix (1); Peptide (1); Site (1) |
Keywords | 3D-structure;Direct protein sequencing;Disulfide bond;Knottin;Protease inhibitor;Secreted;Serine protease inhibitor |
Interact With | |
Induction | |
Subcellular Location | SUBCELLULAR LOCATION: Secreted. |
Modified Residue | |
Post Translational Modification | |
Signal Peptide | |
Structure 3D | NMR spectroscopy (3); X-ray crystallography (6) |
Cross Reference PDB | 1H9H; 1H9I; 1W7Z; 2C4B; 2ETI; 2IT7; 2LET; 6MSL; 6MSU; |
Mapped Pubmed ID | 10409654; 10441159; 16131759; 16337652; 31353240; 8003965; |
Motif | |
Gene Encoded By | |
Mass | 3,089 |
Kinetics | |
Metal Binding | |
Rhea ID | |
Cross Reference Brenda |