Detail Information for IndEnz0002002689
IED ID IndEnz0002002689
Enzyme Type ID protease002689
Protein Name Trypsin inhibitor 2
EETI-II
Trypsin inhibitor II
Gene Name
Organism Ecballium elaterium (Squirting cucumber) (Momordica elaterium)
Taxonomic Lineage cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae eudicotyledons Gunneridae Pentapetalae rosids fabids Cucurbitales Cucurbitaceae Bryonieae Ecballium Ecballium elaterium (Squirting cucumber) (Momordica elaterium)
Enzyme Sequence GCPRILMRCKQDSDCLAGCVCGPNGFCGSP
Enzyme Length 30
Uniprot Accession Number P12071
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number
Enzyme Function FUNCTION: Inhibits trypsin.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Beta strand (2); Disulfide bond (3); Helix (1); Peptide (1); Site (1)
Keywords 3D-structure;Direct protein sequencing;Disulfide bond;Knottin;Protease inhibitor;Secreted;Serine protease inhibitor
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Secreted.
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D NMR spectroscopy (3); X-ray crystallography (6)
Cross Reference PDB 1H9H; 1H9I; 1W7Z; 2C4B; 2ETI; 2IT7; 2LET; 6MSL; 6MSU;
Mapped Pubmed ID 10409654; 10441159; 16131759; 16337652; 31353240; 8003965;
Motif
Gene Encoded By
Mass 3,089
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda