| IED ID | IndEnz0002002707 |
| Enzyme Type ID | protease002707 |
| Protein Name |
Pheromone-processing carboxypeptidase KEX1 EC 3.4.16.6 Carboxypeptidase D |
| Gene Name | KEX1 GLRG_04165 |
| Organism | Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212) (Maize anthracnose fungus) (Glomerella graminicola) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta sordariomyceta Sordariomycetes Hypocreomycetidae Glomerellales Glomerellaceae Colletotrichum Colletotrichum graminicola species complex Colletotrichum graminicola (Maize anthracnose fungus) (Glomerella graminicola) Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212) (Maize anthracnose fungus) (Glomerella graminicola) |
| Enzyme Sequence | MAILSTVPALLFALASWAPTVAAQSAADYFVHELPGAPKEPFIKMHAGHVEVTPEHNGNIFFWHFQNQHIANKQRTVIWLNGGPGCSSEDGALMEIGPYRVKDPDHLEYNNGSWNEFANLLFVDNPVGTGFSFVDTNSYLHELPEMADQFVQFLEKWFAMFPEYEHDDLYISGESYAGQHIPYIAKHILERNKKPGVKTPWQLKGLLMGNAWISPKEQYDAYLKYAYEKKLIEKGSPIALQLEQQWRICRTSLAVTNTVDFTECESVLQKLLEQTAKVNAKGERECINMYDIRLRDTFPSCGMNWPPDLVNLTPYLRKAEVVSALHIKPQKTTGWTECNGAVGSAFRAPNSVPSRDYLPDLLKEVPIVLFSGAEDLICNYMGTEAMIGDMEWNGGKGFELTPGNWAPRRDWTVEGQPAGFWQEARNLTYILFYNSSHMVPFDYARRSRDMLDRFMNVDISSVGGTPTDSRLDGEQGPATSVGDIGKNGTSADAETQKKLDEAKWKAYYRSGEIVLVIVIIAAGAWGWYVWRERRKRRGYSGIMGNTPPIAQRGTTRGLEGFRDRRTGRDVETGDFDESELDDLHVTTPTVEMDKDRYSVGGDSDDEPHDEKPSRSNGGRSGR |
| Enzyme Length | 622 |
| Uniprot Accession Number | E3QDT3 |
| Absorption | |
| Active Site | ACT_SITE 175; /evidence=ECO:0000255|PROSITE-ProRule:PRU10074; ACT_SITE 375; /evidence=ECO:0000255|PROSITE-ProRule:PRU10074; ACT_SITE 437; /evidence=ECO:0000255|PROSITE-ProRule:PRU10074 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=Preferential release of a C-terminal arginine or lysine residue.; EC=3.4.16.6; |
| DNA Binding | |
| EC Number | 3.4.16.6 |
| Enzyme Function | FUNCTION: Protease with a carboxypeptidase B-like function involved in the C-terminal processing of the lysine and arginine residues from protein precursors. Promotes cell fusion and is involved in the programmed cell death (By similarity). {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (3); Chain (1); Compositional bias (1); Glycosylation (4); Region (2); Signal peptide (1); Topological domain (2); Transmembrane (1) |
| Keywords | Apoptosis;Carboxypeptidase;Glycoprotein;Golgi apparatus;Hydrolase;Membrane;Protease;Reference proteome;Signal;Transmembrane;Transmembrane helix |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Golgi apparatus, trans-Golgi network membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..23; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 70,070 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |