Detail Information for IndEnz0002002736
IED ID IndEnz0002002736
Enzyme Type ID protease002736
Protein Name Alpha-1-antiproteinase
Alpha-1-antitrypsin
Alpha-1-proteinase inhibitor
Gene Name
Organism Callosciurus caniceps (Gray-bellied squirrel)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Craniata Vertebrata Gnathostomata (jawed vertebrates) Teleostomi Euteleostomi Sarcopterygii Dipnotetrapodomorpha Tetrapoda Amniota Mammalia Theria Eutheria Boreoeutheria Euarchontoglires Glires (Rodents and rabbits) Rodentia Sciuromorpha (squirrels) Sciuridae Callosciurinae Callosciurini Callosciurus Callosciurus caniceps (Gray-bellied squirrel)
Enzyme Sequence MPSSISWGLLLLAGLCCLAPGSLAGDAQETDASKDDHEHPACHKIAPNLAEFAFDLYRVLARQSNTTNIFFSPVSVATALAALSLGTKGDTHTQILEGLDFNLTEMAETDIHQGFQHLLQTLNRPNNQLQLTTGNGLFIDQSLKLADKFLEDVKNLYHSEAFSTNFTDSEEAKKQINGYVEKGTQGKIVDAVKTLDKNTVFALVNYIFFKGKWEKPFEVEHTTEGDFHVDQATTVKVPMMNRLGRFDLLYCTTLASWVLQMDYLGNATAIFLLPDEGKLQHLEDTITKEILSKFLKNRHTRTVNLYFPKLSITGTYDLRSVLSTLGITKVFSNEADLSGVTEEAPLKLSKGVHKAVLTIDERGTEAAGVTVLEAIPMSLPPDVRFDRPFLIIIYEHYTKSPLFVGKVVNPTQ
Enzyme Length 412
Uniprot Accession Number O54763
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number
Enzyme Function FUNCTION: Inhibitor of serine proteases. {ECO:0000250}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Chain (1); Glycosylation (4); Modified residue (2); Region (1); Signal peptide (1); Site (1)
Keywords Acute phase;Glycoprotein;Phosphoprotein;Protease inhibitor;Secreted;Serine protease inhibitor;Signal
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Secreted.
Modified Residue MOD_RES 33; /note=Phosphoserine; /evidence=ECO:0000250|UniProtKB:P01009; MOD_RES 378; /note=Phosphoserine; /evidence=ECO:0000250|UniProtKB:P01009
Post Translational Modification
Signal Peptide SIGNAL 1..24; /evidence=ECO:0000255
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 45,729
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda