IED ID | IndEnz0002002736 |
Enzyme Type ID | protease002736 |
Protein Name |
Alpha-1-antiproteinase Alpha-1-antitrypsin Alpha-1-proteinase inhibitor |
Gene Name | |
Organism | Callosciurus caniceps (Gray-bellied squirrel) |
Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Craniata Vertebrata Gnathostomata (jawed vertebrates) Teleostomi Euteleostomi Sarcopterygii Dipnotetrapodomorpha Tetrapoda Amniota Mammalia Theria Eutheria Boreoeutheria Euarchontoglires Glires (Rodents and rabbits) Rodentia Sciuromorpha (squirrels) Sciuridae Callosciurinae Callosciurini Callosciurus Callosciurus caniceps (Gray-bellied squirrel) |
Enzyme Sequence | MPSSISWGLLLLAGLCCLAPGSLAGDAQETDASKDDHEHPACHKIAPNLAEFAFDLYRVLARQSNTTNIFFSPVSVATALAALSLGTKGDTHTQILEGLDFNLTEMAETDIHQGFQHLLQTLNRPNNQLQLTTGNGLFIDQSLKLADKFLEDVKNLYHSEAFSTNFTDSEEAKKQINGYVEKGTQGKIVDAVKTLDKNTVFALVNYIFFKGKWEKPFEVEHTTEGDFHVDQATTVKVPMMNRLGRFDLLYCTTLASWVLQMDYLGNATAIFLLPDEGKLQHLEDTITKEILSKFLKNRHTRTVNLYFPKLSITGTYDLRSVLSTLGITKVFSNEADLSGVTEEAPLKLSKGVHKAVLTIDERGTEAAGVTVLEAIPMSLPPDVRFDRPFLIIIYEHYTKSPLFVGKVVNPTQ |
Enzyme Length | 412 |
Uniprot Accession Number | O54763 |
Absorption | |
Active Site | |
Activity Regulation | |
Binding Site | |
Calcium Binding | |
catalytic Activity | |
DNA Binding | |
EC Number | |
Enzyme Function | FUNCTION: Inhibitor of serine proteases. {ECO:0000250}. |
Temperature Dependency | |
PH Dependency | |
Pathway | |
nucleotide Binding | |
Features | Chain (1); Glycosylation (4); Modified residue (2); Region (1); Signal peptide (1); Site (1) |
Keywords | Acute phase;Glycoprotein;Phosphoprotein;Protease inhibitor;Secreted;Serine protease inhibitor;Signal |
Interact With | |
Induction | |
Subcellular Location | SUBCELLULAR LOCATION: Secreted. |
Modified Residue | MOD_RES 33; /note=Phosphoserine; /evidence=ECO:0000250|UniProtKB:P01009; MOD_RES 378; /note=Phosphoserine; /evidence=ECO:0000250|UniProtKB:P01009 |
Post Translational Modification | |
Signal Peptide | SIGNAL 1..24; /evidence=ECO:0000255 |
Structure 3D | |
Cross Reference PDB | - |
Mapped Pubmed ID | - |
Motif | |
Gene Encoded By | |
Mass | 45,729 |
Kinetics | |
Metal Binding | |
Rhea ID | |
Cross Reference Brenda |