Detail Information for IndEnz0002002855
IED ID IndEnz0002002855
Enzyme Type ID protease002855
Protein Name Collagenolytic protease 25 kDa II/III
EC 3.4.21.32
Fragment
Gene Name
Organism Chionoecetes opilio (Crab-beetle)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Protostomia Ecdysozoa Panarthropoda Arthropoda Mandibulata Pancrustacea Crustacea Multicrustacea Malacostraca Eumalacostraca Eucarida Decapoda Pleocyemata Brachyura (short-tailed crabs) Eubrachyura Heterotremata Majoidea Majidae (spider crabs) Chionoecetes Chionoecetes opilio (Crab-beetle)
Enzyme Sequence IVGGQEATPHTWVHQVALFI
Enzyme Length 20
Uniprot Accession Number P34153
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity CATALYTIC ACTIVITY: Reaction=Hydrolysis of proteins, with broad specificity for peptide bonds. Native collagen is cleaved about 75% of the length of the molecule from the N-terminus. Low activity on small molecule substrates of both trypsin and chymotrypsin.; EC=3.4.21.32;
DNA Binding
EC Number 3.4.21.32
Enzyme Function FUNCTION: This enzyme is a serine protease capable of degrading the native triple helix of collagen.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Chain (1); Domain (1); Non-terminal residue (1)
Keywords Collagen degradation;Direct protein sequencing;Hydrolase;Protease;Serine protease
Interact With
Induction
Subcellular Location
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 2,204
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda