Detail Information for IndEnz0002003015
IED ID IndEnz0002003015
Enzyme Type ID protease003015
Protein Name Dipeptidyl-peptidase 6
EC 3.4.22.-
Dipeptidyl-peptidase VI
DPP VI
Endopeptidase II
Gamma-D-glutamyl-L-diamino acid endopeptidase II
Gamma-D-glutamyl-MESO-diaminopimelate peptidase II
Gene Name
Organism Lysinibacillus sphaericus (Bacillus sphaericus)
Taxonomic Lineage cellular organisms Bacteria Terrabacteria group Firmicutes Bacilli Bacillales Bacillaceae Lysinibacillus Lysinibacillus sphaericus (Bacillus sphaericus)
Enzyme Sequence MNAIVIAMMANLYAEPDLHAELVDEILYGMPVQIIEELENDWLYVRTAYRYEGYCQRNDVLFDDAITNTWIQKAQHVIGQRFADVLQEPKIQSTKIITLVKGSILYNVDSDTTSNTPWTAVQLATGEIGYLRSQWLHPKIAEHTFEEHAFRENVVQTALSYIATPYRWGGKSPLGIDCSGLCSMAYLLNGVIIFRDARIVEGFPIKEITIDRMQKGDLLFFPGHVALYLGQTLYVHASLGGNEVNVNSLDEQHPLYRQDLATTITAIGSLF
Enzyme Length 271
Uniprot Accession Number P39043
Absorption
Active Site ACT_SITE 178; /note=Nucleophile; /evidence=ECO:0000255|PROSITE-ProRule:PRU01284; ACT_SITE 224; /note=Proton acceptor; /evidence=ECO:0000255|PROSITE-ProRule:PRU01284; ACT_SITE 236; /evidence=ECO:0000255|PROSITE-ProRule:PRU01284
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number 3.4.22.-
Enzyme Function FUNCTION: Involved in cell sporulation. Hydrolyzes gamma-D-Glu-L-(meso)A2pm linkages only in those peptide units that have a free N-terminal L-alanine.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (3); Chain (1); Domain (3)
Keywords Cytoplasm;Direct protein sequencing;Hydrolase;Protease;Sporulation;Thiol protease
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Cytoplasm.
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 30,604
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda