| IED ID | IndEnz0002003043 |
| Enzyme Type ID | protease003043 |
| Protein Name |
Alpha-2-HS-glycoprotein Fetuin-A |
| Gene Name | AHSG FETUA |
| Organism | Cavia porcellus (Guinea pig) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Craniata Vertebrata Gnathostomata (jawed vertebrates) Teleostomi Euteleostomi Sarcopterygii Dipnotetrapodomorpha Tetrapoda Amniota Mammalia Theria Eutheria Boreoeutheria Euarchontoglires Glires (Rodents and rabbits) Rodentia Hystricomorpha Caviidae (cavies) Cavia (guinea pigs) Cavia porcellus (Guinea pig) |
| Enzyme Sequence | MKFFVLFLCLVQLWGCHSTPVVLGLEERNPACDDPETEAAALAGVDYLNQHVRWGYKHVLNQIDKVRVWPRRPSGEVYELEFDTLETTCHALDITPLANCSVRTVTQHAVEGDCDMHVLKQDGQFSVVFAKCESTPDSREDVRKVCPQCPLLTPVNNTKVVHAANAALAAFNAQNNGSHFELLEISRAQLVPLPVSTYVEFAVVATDCAAADGTDPACSGPPKKQYGFCKATVAEKLGGEEVSVTCTVFPTQPVAPLPQPDAASSANPPPAADPAVSPPSSPSVPVDSVALGPKRVLLPPPVHREHYNLRYSFPDVDSASGEAFGPRQKPKVTHPGVASGVGPVPPPPCPGRIRHFKI |
| Enzyme Length | 358 |
| Uniprot Accession Number | O70159 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | |
| Enzyme Function | |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Compositional bias (1); Disulfide bond (6); Domain (2); Glycosylation (3); Modified residue (5); Region (2); Signal peptide (1) |
| Keywords | Disulfide bond;Glycoprotein;Phosphoprotein;Protease inhibitor;Reference proteome;Repeat;Secreted;Signal |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Secreted {ECO:0000250}. |
| Modified Residue | MOD_RES 134; /note=Phosphoserine; /evidence=ECO:0000250|UniProtKB:P02765; MOD_RES 135; /note=Phosphothreonine; /evidence=ECO:0000250|UniProtKB:P29699; MOD_RES 138; /note=Phosphoserine; /evidence=ECO:0000250|UniProtKB:P02765; MOD_RES 318; /note=Phosphoserine; /evidence=ECO:0000250|UniProtKB:P02765; MOD_RES 320; /note=Phosphoserine; /evidence=ECO:0000250|UniProtKB:P02765 |
| Post Translational Modification | PTM: Phosphorylated by FAM20C in the extracellular medium. {ECO:0000250|UniProtKB:P02765}. |
| Signal Peptide | SIGNAL 1..18; /evidence=ECO:0000250 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 38,472 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |