| IED ID | IndEnz0002003175 |
| Enzyme Type ID | protease003175 |
| Protein Name |
Cysteine proteinase 7 EC 3.4.22.- Proteinase 1 |
| Gene Name | cprG CP7 DDB_G0279187 |
| Organism | Dictyostelium discoideum (Slime mold) |
| Taxonomic Lineage | cellular organisms Eukaryota Amoebozoa Evosea Eumycetozoa Dictyostelia (dictyostelid cellular slime molds) Dictyosteliales Dictyosteliaceae Dictyostelium Dictyostelium discoideum (Slime mold) |
| Enzyme Sequence | MKVLSALCVLLVSVATAKQQLSEVEYRNAFTNWMIAHQRHYSSEEFNGRYNIFKANMDYVNEWNTKGSETVLGLNVFADISNEEYRATYLGTPFDASSLEMTESDKIFDASAQVDWRTQGAVTPIKNQGQCGGCWSFSTTGATEGAQYLANGKKNLVSLSEQNLIDCSGSYGNNGCEGGLMTLAFEYIINNKGIDTESSYPYTAEDGKKCKFNPKNVAAQLSSYVNVTSGSESDLAAKVTQGPTSVAIDASNQSFQLYVSGIYNEPACSSTQLDHGVLAVGFGTGSGSSGSHGGSQSQSAGSDSQSAGSESSQSESGSQSQSESGSQSQSQSGSQSFSGSLYSGSYSGSQSGSQSGNSGAAVKQTGAGSGSGSGSGSGSGSGSGSVSGSASGSASGSASGSSSGSNSNGGVYPTAGDYWIVKNSWGTSWGMDGYILMTKGNNNQCGIATMASRPTAVASL |
| Enzyme Length | 460 |
| Uniprot Accession Number | Q94504 |
| Absorption | |
| Active Site | ACT_SITE 134; /evidence=ECO:0000250; ACT_SITE 275; /evidence=ECO:0000250; ACT_SITE 423; /evidence=ECO:0000250 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.22.- |
| Enzyme Function | |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (3); Chain (1); Disulfide bond (3); Glycosylation (2); Propeptide (1); Region (1); Signal peptide (1) |
| Keywords | Disulfide bond;Glycoprotein;Hydrolase;Lysosome;Phosphoprotein;Protease;Reference proteome;Signal;Thiol protease;Zymogen |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Lysosome {ECO:0000305}. |
| Modified Residue | |
| Post Translational Modification | PTM: Glycosylated; contains GlcNAc-alpha-1-P-Ser residues. Also N-glycosylated. {ECO:0000269|PubMed:9056234}. |
| Signal Peptide | SIGNAL 1..17; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | 20422638; 22120990; 7639520; |
| Motif | |
| Gene Encoded By | |
| Mass | 47,166 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |