| IED ID | IndEnz0002003179 |
| Enzyme Type ID | protease003179 |
| Protein Name |
Probable aspartyl aminopeptidase EC 3.4.11.21 |
| Gene Name | RCOM_1506700 |
| Organism | Ricinus communis (Castor bean) |
| Taxonomic Lineage | cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae eudicotyledons Gunneridae Pentapetalae rosids fabids Malpighiales Euphorbiaceae Acalyphoideae Acalypheae Ricinus Ricinus communis (Castor bean) |
| Enzyme Sequence | MAKQDSQTEGISIDSDLINFLNASPTAFHAIDEAKKRLKHSGYVQVSERDDWKLELGKRYFFTRNHSTIVAFAIGKKYVAGNGFYVVGAHTDSPCIKLKPVSKVTKSGYLEVGVQPYGGGLWHTWFDRDLAVAGRVIVREEKHGSVSYSHRLVRIEEPIMRVPTLAIHLDRNVNTDGFKVNTQSHLLPVLATSVKAELSKVVAENGTVGNDEETDGMKSSKGTTNANSKHHSLLLQMIAGQIGCNGSDICDFELQACDTQPSVIAGAAKEFIFSGRLDNLCMSFCSLKALIDATASDSHLENESGVRMVALFDHEEVGSDSAQGAGSPVMFDALSRITSTFNSDSKLLRKAIQKSFLVSADMAHALHPNYADKHEENHQPRMHGGLVIKHNANQRYATNSVTSFLFKEIASKHNLPVQDFVVRNDMPCGSTIGPILASGVGIRTVDVGAPQLSMHSIREMCAVDDVKYSYEHFKAFFEDFSHLDSKITVDM |
| Enzyme Length | 491 |
| Uniprot Accession Number | B9RAJ0 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | BINDING 168; /note=Substrate; /evidence=ECO:0000250; BINDING 315; /note=Substrate; /evidence=ECO:0000250; BINDING 361; /note=Substrate; /evidence=ECO:0000250; BINDING 364; /note=Substrate; /evidence=ECO:0000250; BINDING 389; /note=Substrate; /evidence=ECO:0000250; BINDING 396; /note=Substrate; /evidence=ECO:0000250 |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=Release of an N-terminal aspartate or glutamate from a peptide, with a preference for aspartate.; EC=3.4.11.21; |
| DNA Binding | |
| EC Number | 3.4.11.21 |
| Enzyme Function | FUNCTION: Likely to play an important role in intracellular protein and peptide metabolism. {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Binding site (6); Chain (1); Erroneous gene model prediction (1); Frameshift (1); Metal binding (6) |
| Keywords | Aminopeptidase;Cytoplasm;Hydrolase;Metal-binding;Metalloprotease;Protease;Reference proteome;Zinc |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 53,907 |
| Kinetics | |
| Metal Binding | METAL 90; /note=Zinc 1; /evidence=ECO:0000250; METAL 278; /note=Zinc 1; /evidence=ECO:0000250; METAL 278; /note=Zinc 2; /evidence=ECO:0000250; METAL 316; /note=Zinc 2; /evidence=ECO:0000250; METAL 361; /note=Zinc 1; /evidence=ECO:0000250; METAL 455; /note=Zinc 2; /evidence=ECO:0000250 |
| Rhea ID | |
| Cross Reference Brenda |