Detail Information for IndEnz0002003243
IED ID IndEnz0002003243
Enzyme Type ID protease003243
Protein Name Protease HtpX homolog
EC 3.4.24.-
Gene Name htpX LB_174
Organism Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)
Taxonomic Lineage cellular organisms Bacteria Spirochaetes Spirochaetia Leptospirales Leptospiraceae Leptospira Leptospira interrogans Leptospira interrogans serovar Lai Leptospira interrogans serogroup Icterohaemorrhagiae serovar Lai (strain 56601)
Enzyme Sequence MWFKRIGLFLLTNILVVVTISIVTSVLGIGPYLDANGINLSSLLVFCFLWGMGGAFVSLLLSKFMAKMMMGVQVIDPRSASGAERELYSRVERLARTANLPMPEVGIYHSPEVNAFATGPSKSSSLVAVSSGLLQTMDNAEVEGVLAHELAHVANGDMVTMTLIQGVVNAFVMFFSRIISYALSTMVKDELQYTVRLIANIVLSILFSILGSIIVAYFSRTREYRADAGGAKLAGRQNMIAALEKLKRTFDAPEDERGREALATMKISGHNKWMALFSTHPPLEARIAALKNSGY
Enzyme Length 295
Uniprot Accession Number Q8EXN4
Absorption
Active Site ACT_SITE 149; /evidence=ECO:0000255|HAMAP-Rule:MF_00188
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number 3.4.24.-
Enzyme Function
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (1); Chain (1); Metal binding (3); Transmembrane (4)
Keywords Cell inner membrane;Cell membrane;Hydrolase;Membrane;Metal-binding;Metalloprotease;Protease;Reference proteome;Transmembrane;Transmembrane helix;Zinc
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-Rule:MF_00188}; Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_00188}.
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 32,190
Kinetics
Metal Binding METAL 148; /note=Zinc; catalytic; /evidence=ECO:0000255|HAMAP-Rule:MF_00188; METAL 152; /note=Zinc; catalytic; /evidence=ECO:0000255|HAMAP-Rule:MF_00188; METAL 223; /note=Zinc; catalytic; /evidence=ECO:0000255|HAMAP-Rule:MF_00188
Rhea ID
Cross Reference Brenda