Detail Information for IndEnz0002003280
IED ID IndEnz0002003280
Enzyme Type ID protease003280
Protein Name Cathepsin B-like cysteine proteinase 5
EC 3.4.22.-
Cysteine protease-related 5
Gene Name cpr-5 W07B8.5
Organism Caenorhabditis elegans
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Protostomia Ecdysozoa Nematoda (roundworms) Chromadorea Rhabditida Rhabditina Rhabditomorpha Rhabditoidea Rhabditidae Peloderinae Caenorhabditis Caenorhabditis elegans
Enzyme Sequence MWKLSAILLVAAASAVVIPGHREAPALTGQALIDYVNSAQKLWTAGHQVIPKEKITKKLMDVKYLVPHKDEDIVATEVSDAIPDHFDARDQWPNCMSINNIRDQSDCGSCWAFAAAEAISDRTCIASNGAVNTLLSSEDLLSCCTGMFSCGNGCEGGYPIQAWKWWVKHGLVTGGSYETQFGCKPYSIAPCGETVNGVKWPACPEDTEPTPKCVDSCTSKNNYATPYLQDKHFGSTAYAVGKKVEQIQTEILTNGPIEVAFTVYEDFYQYTTGVYVHTAGASLGGHAVKILGWGVDNGTPYWLVANSWNVAWGEKGYFRIIRGLNECGIEHSAVAGIPDLARHN
Enzyme Length 344
Uniprot Accession Number P43509
Absorption
Active Site ACT_SITE 110; /evidence=ECO:0000250; ACT_SITE 286; /evidence=ECO:0000250; ACT_SITE 306; /evidence=ECO:0000250
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number 3.4.22.-
Enzyme Function
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (3); Chain (1); Disulfide bond (6); Propeptide (1); Signal peptide (1)
Keywords Disulfide bond;Hydrolase;Protease;Reference proteome;Signal;Thiol protease;Zymogen
Interact With
Induction
Subcellular Location
Modified Residue
Post Translational Modification
Signal Peptide SIGNAL 1..15; /evidence=ECO:0000255
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID 14704431; 21177967; 22286215; 22560298; 23800452; 25487147; 29348603;
Motif
Gene Encoded By
Mass 37,391
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda