IED ID | IndEnz0002003280 |
Enzyme Type ID | protease003280 |
Protein Name |
Cathepsin B-like cysteine proteinase 5 EC 3.4.22.- Cysteine protease-related 5 |
Gene Name | cpr-5 W07B8.5 |
Organism | Caenorhabditis elegans |
Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Protostomia Ecdysozoa Nematoda (roundworms) Chromadorea Rhabditida Rhabditina Rhabditomorpha Rhabditoidea Rhabditidae Peloderinae Caenorhabditis Caenorhabditis elegans |
Enzyme Sequence | MWKLSAILLVAAASAVVIPGHREAPALTGQALIDYVNSAQKLWTAGHQVIPKEKITKKLMDVKYLVPHKDEDIVATEVSDAIPDHFDARDQWPNCMSINNIRDQSDCGSCWAFAAAEAISDRTCIASNGAVNTLLSSEDLLSCCTGMFSCGNGCEGGYPIQAWKWWVKHGLVTGGSYETQFGCKPYSIAPCGETVNGVKWPACPEDTEPTPKCVDSCTSKNNYATPYLQDKHFGSTAYAVGKKVEQIQTEILTNGPIEVAFTVYEDFYQYTTGVYVHTAGASLGGHAVKILGWGVDNGTPYWLVANSWNVAWGEKGYFRIIRGLNECGIEHSAVAGIPDLARHN |
Enzyme Length | 344 |
Uniprot Accession Number | P43509 |
Absorption | |
Active Site | ACT_SITE 110; /evidence=ECO:0000250; ACT_SITE 286; /evidence=ECO:0000250; ACT_SITE 306; /evidence=ECO:0000250 |
Activity Regulation | |
Binding Site | |
Calcium Binding | |
catalytic Activity | |
DNA Binding | |
EC Number | 3.4.22.- |
Enzyme Function | |
Temperature Dependency | |
PH Dependency | |
Pathway | |
nucleotide Binding | |
Features | Active site (3); Chain (1); Disulfide bond (6); Propeptide (1); Signal peptide (1) |
Keywords | Disulfide bond;Hydrolase;Protease;Reference proteome;Signal;Thiol protease;Zymogen |
Interact With | |
Induction | |
Subcellular Location | |
Modified Residue | |
Post Translational Modification | |
Signal Peptide | SIGNAL 1..15; /evidence=ECO:0000255 |
Structure 3D | |
Cross Reference PDB | - |
Mapped Pubmed ID | 14704431; 21177967; 22286215; 22560298; 23800452; 25487147; 29348603; |
Motif | |
Gene Encoded By | |
Mass | 37,391 |
Kinetics | |
Metal Binding | |
Rhea ID | |
Cross Reference Brenda |