Detail Information for IndEnz0002003410
IED ID IndEnz0002003410
Enzyme Type ID protease003410
Protein Name Leucine aminopeptidase 1
EC 3.4.11.-
Leucyl aminopeptidase 1
LAP1
Gene Name lap1 AN7035
Organism Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta Eurotiomycetes Eurotiomycetidae Eurotiales (green and blue molds) Aspergillaceae Aspergillus Aspergillus subgen. Nidulantes Emericella nidulans (Aspergillus nidulans) Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
Enzyme Sequence MKLSTALVLGATATGAWSYAIPQLEQEVLELPETHYEQQEKYLIELSPYQTRWVTEEEKWALKLDGVNFIDITEDRNYGLFPTLDAGSYVNYPQKMGYVDTVKGLIAGLSMDNMRKDLENFTSFHTRYYKSSSGVESAQWLYDQVSKVVRDSGADKFGATVQKFDHSWGQFSIIARIPGLSKKTVVLGAHQDSINLFLPSFLGAPGADDDGSGTVTILEALRGLLKSDIVAHGQSPNTIEFHWYSAEEGGMLGSQAIFSKYKKNQADVKAMLQQDMTGYVQGTKHAGQKESIGVMTDFVDPALTSFLKNTIVTYCAIPFVETKCGYACSDHTSASKYGYPSAMATESTMENSNKHIHTTDDKISYLSFDHMLEHAKLTLGFAYELAFAAL
Enzyme Length 390
Uniprot Accession Number Q5AXE5
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number 3.4.11.-
Enzyme Function FUNCTION: Extracellular aminopeptidase that allows assimilation of proteinaceous substrates. {ECO:0000250}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Chain (1); Disulfide bond (1); Glycosylation (1); Metal binding (6); Propeptide (1); Signal peptide (1)
Keywords Aminopeptidase;Disulfide bond;Glycoprotein;Hydrolase;Metal-binding;Protease;Reference proteome;Secreted;Signal;Zinc;Zymogen
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
Modified Residue
Post Translational Modification
Signal Peptide SIGNAL 1..18; /evidence=ECO:0000255
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 43,225
Kinetics
Metal Binding METAL 190; /note=Zinc 1; /evidence=ECO:0000250; METAL 209; /note=Zinc 1; /evidence=ECO:0000250; METAL 209; /note=Zinc 2; catalytic; /evidence=ECO:0000250; METAL 248; /note=Zinc 2; catalytic; /evidence=ECO:0000250; METAL 275; /note=Zinc 1; /evidence=ECO:0000250; METAL 357; /note=Zinc 2; catalytic; /evidence=ECO:0000250
Rhea ID
Cross Reference Brenda