Detail Information for IndEnz0002003427
IED ID IndEnz0002003427
Enzyme Type ID protease003427
Protein Name Protease HtpX
EC 3.4.24.-
Heat shock protein HtpX
Gene Name htpX YPDSF_1742
Organism Yersinia pestis (strain Pestoides F)
Taxonomic Lineage cellular organisms Bacteria Proteobacteria Gammaproteobacteria Enterobacterales Yersiniaceae Yersinia Yersinia pseudotuberculosis complex Yersinia pestis Yersinia pestis (strain Pestoides F)
Enzyme Sequence MMRIALFLLTNLAVMLVFGLVLSLTGIQSSSVQGLMIMAGLFGFGGAFVSLLMSKWMALRSVGGEVIERPRNETEYWLLETVRRQSQQVGIAMPQVAIYQAPDINAFATGARRDASLVAVSTGLLQNMSRDEAEAVIAHEISHVANGDMVTMTLIQGVVNTFVIFISRLIAQIAAGFLSGDRDGESNSPGNPMVYFAVSMVLELVFGILASIITMWFSRHREFHADAGSAKLVGREKMIAALQRLKTSYEPQEAGSMMAFCINGKSKTFSELFMSHPPLDKRIEALRSGQYLK
Enzyme Length 293
Uniprot Accession Number A4TLG5
Absorption
Active Site ACT_SITE 140; /evidence=ECO:0000255|HAMAP-Rule:MF_00188
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number 3.4.24.-
Enzyme Function
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (1); Chain (1); Metal binding (3); Transmembrane (4)
Keywords Cell inner membrane;Cell membrane;Hydrolase;Membrane;Metal-binding;Metalloprotease;Protease;Stress response;Transmembrane;Transmembrane helix;Zinc
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-Rule:MF_00188}; Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_00188}.
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 32,064
Kinetics
Metal Binding METAL 139; /note=Zinc; catalytic; /evidence=ECO:0000255|HAMAP-Rule:MF_00188; METAL 143; /note=Zinc; catalytic; /evidence=ECO:0000255|HAMAP-Rule:MF_00188; METAL 222; /note=Zinc; catalytic; /evidence=ECO:0000255|HAMAP-Rule:MF_00188
Rhea ID
Cross Reference Brenda