| IED ID | IndEnz0002003462 |
| Enzyme Type ID | protease003462 |
| Protein Name |
Chymotrypsin-2 EC 3.4.21.1 Chymotrypsin II |
| Gene Name | |
| Organism | Vespa orientalis (Oriental hornet) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Protostomia Ecdysozoa Panarthropoda Arthropoda Mandibulata Pancrustacea Hexapoda Insecta Dicondylia Pterygota (winged insects) Neoptera Endopterygota Hymenoptera Apocrita (wasps ants and bees) Aculeata Vespoidea Vespidae (wasps) Vespinae (hornets and yellowjackets) Vespa Vespa orientalis (Oriental hornet) |
| Enzyme Sequence | IVGGTNAPRGKYPYQVSLRAPKHFCGGSISKRYVLTAAHCLVGKSEHQVTVGSVLLNKEEAVYNAKELIVNKNYNSIRLINDIGLIRVSKDISFTQLVQPVKLPVSNTIKAGDPVVLTGWGRIYVNGPIPNNLQQITLSIVNQQTCKSKHWGLTDSQICTFTKRGEGACHGDSGGPLVANGVQIGIVSYGHPCAIGSPNVFTRVYSFLDWIQKNQL |
| Enzyme Length | 216 |
| Uniprot Accession Number | P00768 |
| Absorption | |
| Active Site | ACT_SITE 39; /note=Charge relay system; /evidence=ECO:0000269|PubMed:6786354; ACT_SITE 82; /note=Charge relay system; /evidence=ECO:0000269|PubMed:6786354; ACT_SITE 173; /note=Charge relay system; /evidence=ECO:0000269|PubMed:6786354 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=Preferential cleavage: Tyr-|-Xaa, Trp-|-Xaa, Phe-|-Xaa, Leu-|-Xaa.; EC=3.4.21.1; Evidence={ECO:0000255|PROSITE-ProRule:PRU10078, ECO:0000255|PROSITE-ProRule:PRU10079}; |
| DNA Binding | |
| EC Number | 3.4.21.1 |
| Enzyme Function | |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (3); Chain (1); Disulfide bond (3); Domain (1) |
| Keywords | Direct protein sequencing;Disulfide bond;Hydrolase;Protease;Secreted;Serine protease |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Secreted, extracellular space. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 23,471 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |