| IED ID | IndEnz0002003496 |
| Enzyme Type ID | protease003496 |
| Protein Name |
Cysteine proteinase 4 EC 3.4.22.- |
| Gene Name | cprD CP4 DDB_G0278721 |
| Organism | Dictyostelium discoideum (Slime mold) |
| Taxonomic Lineage | cellular organisms Eukaryota Amoebozoa Evosea Eumycetozoa Dictyostelia (dictyostelid cellular slime molds) Dictyosteliales Dictyosteliaceae Dictyostelium Dictyostelium discoideum (Slime mold) |
| Enzyme Sequence | MRVLSFLCLLLVSYASAKQQFSELQYRNAFTNWMQAHQRTYSSEEFNARYQIFKSNMDYVHQWNSKGGETVLGLNVFADITNQEYRTTYLGTPFDGSALIGTEEEKIFSTPAPTVDWRAQGAVTPIKNQGQCGGCWSFSTTGSTEGAHFIASGTKKDLVSLSEQNLIDCSKSYGNNGCEGGLMTLAFEYIINNKGIDTESSYPYTAEDGKECKFKTSNIGAQIVSYQNVTSGSEASLQSASNNAPVSVAIDASNESFQLYESGIYYEPACSPTQLDHGVLVVGYGSGSSSSSGSSSGKSSSSSSTGGKTSSSSSSGKASSSSSGKASSSSSSGKTSSAASSTSGSQSGSQSGSQSGQSTGSQSGQTSASGQASASGSGSGSGSGSGSGSGSGAVEASSGNYWIVKNSWGTSWGMDGYIFMSKDRNNNCGIATMASFPTASSN |
| Enzyme Length | 442 |
| Uniprot Accession Number | P54639 |
| Absorption | |
| Active Site | ACT_SITE 135; /evidence=ECO:0000250; ACT_SITE 277; /evidence=ECO:0000250; ACT_SITE 406; /evidence=ECO:0000250 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.22.- |
| Enzyme Function | |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (3); Chain (1); Disulfide bond (3); Glycosylation (2); Propeptide (1); Region (1); Sequence conflict (2); Signal peptide (1) |
| Keywords | Disulfide bond;Glycoprotein;Hydrolase;Lysosome;Protease;Reference proteome;Repeat;Signal;Thiol protease;Zymogen |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Lysosome. |
| Modified Residue | |
| Post Translational Modification | PTM: Glycosylated; contains GlcNAc-alpha-1-P-Ser residues and fucose. |
| Signal Peptide | SIGNAL 1..17; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | 10651904; 15196949; 16215182; 17644489; 18559084; 20422638; 22120990; 24373846; 26028264; 7639520; 9056234; 9584128; |
| Motif | |
| Gene Encoded By | |
| Mass | 45,690 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |