| IED ID | IndEnz0002003663 |
| Enzyme Type ID | protease003663 |
| Protein Name |
Xaa-Pro aminopeptidase 1 EC 3.4.11.9 Aminoacylproline aminopeptidase I Aminopeptidase P I APP PEPP I X-Pro aminopeptidase I Xaa-Pro aminopeptidase I |
| Gene Name | pepPI pepP SCO3970 SCBAC25E3.07c |
| Organism | Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) |
| Taxonomic Lineage | cellular organisms Bacteria Terrabacteria group Actinobacteria Actinomycetia (high G+C Gram-positive bacteria) Streptomycetales Streptomycetaceae Streptomyces Streptomyces albidoflavus group Streptomyces coelicolor Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) |
| Enzyme Sequence | MAEELTPENPAIPETPEETEEPIKQRKNGLYPGVSDELAENMQSGWADTELHDLEPIAQAAETAARRAALSARFPGERLVIPAGNLKTRSNDTEYSFRASVEYAYLTGNQTEDGVLVMEPEGDGHAATIYLLPRSDRENGEFWLDGQGELWVGRRHSLAEAGELYGIPASDVRELAGSLREATGPVRVVRGFDAGIEAALTDKVTAERDEELRVFLSEARLVKDEFEIGELQKAVDSTVRGFEDVVKVLDRAEATSERYIEGTFFLRARVEGNDVGYGSICAAGPHACTLHWVRNDGPVRSGDLLLLDAGVETHTYYTADVTRTLPISGTYSELQKKIYDAVYDAQEAGIAAVRPGAKYRDFHDASQRVLAERLVEWGLVEGPVERVLELGLQRRWTLHGTGHMLGMDVHDCAAARVESYVDGTLEPGMVLTVEPGLYFQADDLTVPEEYRGIGVRIEDDILVTADGNRNLSAGLPRRSDEVEEWMAALKG |
| Enzyme Length | 491 |
| Uniprot Accession Number | P0A3Z1 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=Release of any N-terminal amino acid, including proline, that is linked to proline, even from a dipeptide or tripeptide.; EC=3.4.11.9; |
| DNA Binding | |
| EC Number | 3.4.11.9 |
| Enzyme Function | |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Initiator methionine (1); Metal binding (7); Region (1) |
| Keywords | Aminopeptidase;Hydrolase;Manganese;Metal-binding;Metalloprotease;Protease;Reference proteome |
| Interact With | |
| Induction | |
| Subcellular Location | |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 54,048 |
| Kinetics | |
| Metal Binding | METAL 308; /note=Manganese 2; /evidence=ECO:0000250; METAL 320; /note=Manganese 1; /evidence=ECO:0000250; METAL 320; /note=Manganese 2; /evidence=ECO:0000250; METAL 403; /note=Manganese 1; /evidence=ECO:0000250; METAL 434; /note=Manganese 1; /evidence=ECO:0000250; METAL 458; /note=Manganese 1; /evidence=ECO:0000250; METAL 458; /note=Manganese 2; /evidence=ECO:0000250 |
| Rhea ID | |
| Cross Reference Brenda |