Detail Information for IndEnz0002003769
IED ID IndEnz0002003769
Enzyme Type ID protease003769
Protein Name Mitochondrial-processing peptidase subunit alpha
Alpha-MPP
Inactive zinc metalloprotease alpha
Gene Name
Organism Blastocladiella emersonii (Aquatic fungus)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Fungi Fungi incertae sedis Blastocladiomycota Blastocladiomycota incertae sedis Blastocladiomycetes Blastocladiales Blastocladiaceae Blastocladiella Blastocladiella emersonii (Aquatic fungus)
Enzyme Sequence MSPAAQLAKAAARSTCMTRLPSGIRVATAPSNSHFAAVGVYVDAGPIYETSIDRGVSHFVSSLAFKSTHGATESQVLKTMAGLGGNLFCTATRESILYQGSVLHHDLPRTVQLLADTTLRPALTEEEIAERRATIAFEAEDLHSRPDAFIGEMMHAVAFGGRGLGNSIFCEPQRARNMTSDTIREYFATYLHPSRMVVAGTGVAHAELVDLVSKAFVPSSTRAPSSVTHSDIETAYVGGSHQLVIPKPPPTHPNYEQTLTHVQVAFPVPPFTHPDMFPVSTLQVLMGGGGAFSAGGPGKGMYSRLYTNVLNRYRWMESCAAFQHAYSSTSLFGISASCVPSFNPHLCNVLAGEFVHMARNLSDEEVARAKNQLKSSLLMNLESQVITVEDIGRQVLAQNQRLEPLELVNNISAVTRDDLVRVAEALVAKPPTMVAVGEDLTKLTDIKETLAAFNASGEALQPVGSAGSFGRVTM
Enzyme Length 474
Uniprot Accession Number P97997
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number
Enzyme Function FUNCTION: Substrate recognition and binding subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins. {ECO:0000250|UniProtKB:P11914}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Chain (1); Transit peptide (1)
Keywords Membrane;Mitochondrion;Mitochondrion inner membrane;Transit peptide
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000269|PubMed:10400583}.
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 50,856
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda