Detail Information for IndEnz0002003933
IED ID IndEnz0002003933
Enzyme Type ID protease003933
Protein Name Zinc carboxypeptidase A 1
EC 3.4.17.-
Gene Name CG17633
Organism Drosophila melanogaster (Fruit fly)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Protostomia Ecdysozoa Panarthropoda Arthropoda Mandibulata Pancrustacea Hexapoda Insecta Dicondylia Pterygota (winged insects) Neoptera Endopterygota Diptera Brachycera Muscomorpha Eremoneura Cyclorrhapha Schizophora Acalyptratae Ephydroidea Drosophilidae (pomace flies) Drosophilinae Drosophilini Drosophila (fruit flies) Sophophora melanogaster group melanogaster subgroup Drosophila melanogaster (Fruit fly)
Enzyme Sequence MSLNKCLLFALLAIVASASVSAERVRYDNYRMYKVNSENAKQLEVLKDLEGSSDSIMFLDGVHLVGADIQIIVAPHKVPDFLEILGKSEIKYELQSRDVQKSLDEIDEKVAIKGRATTAYNWAQYYELDDTYAWLQSLAQTNPGVVTLIEGGKTYQGRSILGVKITKGGETINGKAKPGIFLEAGIHAREWIAPAAATFIINQLLTSEVENIKELAENYTWYVLPHANPDGYVYTHTTNRLWRKTRTPYGSCFGADPNRNWGFHWNEVGASSSACSDTYAGPSAFSEIETLSLSKFIEGLKGKVQLYLSLHAYSQYLLYPYGHTSDLPDNVADFEKVFDASIAAVNKRYGTTYTGGNIYDAIYPAAGASVDWAYGTQDVRMAFCYELRPSSTSYLTGFKLPAEQIVPASEELLDSIVAMATEVKSLGYFD
Enzyme Length 430
Uniprot Accession Number Q9VL86
Absorption
Active Site ACT_SITE 386; /note=Proton donor/acceptor; /evidence=ECO:0000250|UniProtKB:P00730
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number 3.4.17.-
Enzyme Function
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (1); Chain (1); Disulfide bond (1); Metal binding (3); Sequence conflict (1); Signal peptide (1)
Keywords Carboxypeptidase;Disulfide bond;Hydrolase;Metal-binding;Metalloprotease;Protease;Reference proteome;Secreted;Signal;Zinc
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
Modified Residue
Post Translational Modification
Signal Peptide SIGNAL 1..22; /evidence=ECO:0000255
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID 11404335; 14680800; 16914392; 18241855; 19033155; 19765174; 20371351; 21074052; 23071443; 23087838; 23944235; 25687947; 25848931; 26219626; 27058248; 27357258; 30892991; 31722958;
Motif
Gene Encoded By
Mass 47,661
Kinetics
Metal Binding METAL 187; /note=Zinc; catalytic; /evidence=ECO:0000250|UniProtKB:P00730; METAL 190; /note=Zinc; catalytic; /evidence=ECO:0000250|UniProtKB:P00730; METAL 311; /note=Zinc; catalytic; /evidence=ECO:0000250|UniProtKB:P00730
Rhea ID
Cross Reference Brenda