IED ID | IndEnz0002003942 |
Enzyme Type ID | protease003942 |
Protein Name |
Capsid protein Coat protein CP VP1 |
Gene Name | ORF2 |
Organism | San Miguel sea lion virus serotype 1 (SMSV-1) (SMSV serotype 1) |
Taxonomic Lineage | Viruses Riboviria Orthornavirae Pisuviricota Pisoniviricetes Picornavirales Caliciviridae Vesivirus Vesicular exanthema of swine virus (VESV) San Miguel sea lion virus serotype 1 (SMSV-1) (SMSV serotype 1) |
Enzyme Sequence | MATTHTLLSFDDLEFLLHKKDLTDLYGERCGTLNLVINPYDLFLPDDLDDDWCDDPFNCCFSDVYTSIGTEYSYIDPPDLIYEEHCATNGHWPDGTPCEPILPPFVIEGTHHYYATKPGEAVSGILSKLGSAWDPDLQSTVDTKPDFVFRAESDGPGGADIVTEEQGTVVQQQPVPAQSALTTLAAASTGKTVDCEWTTFFSYHTAVNWSTTEAQGKILFSRALSPELNPYLRHISSLYSTWSGGIDVRFTVSGSGVFGGKLAALIVPPGIEPVESPTMLQYPHVLFDARQTEPVIFTIPDIRKTLYHSMDDTDTTRLVIMVYNELINPYEQSEPKSSCSITVETRPSSDFTFSLLKPPGSLLKHGSIPSDLIPRNSRHWMGNRWWSTIDGFVVQPRVFQSNRHFDFDSTTTGWSTPYYIPIEVTLEKLDRGGQYFKVTDTEKSLVPGLPDGWPDTTIPTAMTASNGNYDYTVAEYRITNNGTHFKGFYIMGNLTTKVKGSDNLGETQQTSRTLFASVGNYKDQNTINPTHKITSNSLVVYDANNVSAATAKTTTWHSTMSHLGYVLVDESPVGSDSTKVVRIATLPEAFTNGGNFPVFFTNKIQIGHFDRAHTKCFNSQVLMTSQKLAENHYTLPPDSLLVYRITDAASSWFDLGINHDGFSYVGISTIPELDFPLTFNLHGVQLAKVKLASKVKTSKTTI |
Enzyme Length | 702 |
Uniprot Accession Number | P36284 |
Absorption | |
Active Site | |
Activity Regulation | |
Binding Site | |
Calcium Binding | |
catalytic Activity | |
DNA Binding | |
EC Number | |
Enzyme Function | FUNCTION: Capsid protein self assembles to form an icosahedral capsid with a T=3 symmetry, about 38 nm in diameter, and consisting of 180 capsid proteins. A smaller form of capsid with a diameter of 23 nm might be capsid proteins assembled as icosahedron with T=1 symmetry. The capsid encapsulate the genomic RNA and VP2 proteins. Attaches virion to target cells by binding to feline junctional adhesion molecule A (F11R) and/or to alpha-2,6-linked sialic acid. Once attached, the virion is endocytosed. Acidification of the endosome induces conformational change of capsid protein thereby injecting virus genomic RNA into host cytoplasm (By similarity). {ECO:0000250}. |
Temperature Dependency | |
PH Dependency | |
Pathway | |
nucleotide Binding | |
Features | Chain (1); Propeptide (1); Site (1) |
Keywords | Capsid protein;Host cytoplasm;T=3 icosahedral capsid protein;Virion |
Interact With | |
Induction | |
Subcellular Location | SUBCELLULAR LOCATION: Virion. Host cytoplasm {ECO:0000250}. |
Modified Residue | |
Post Translational Modification | PTM: Cleaved by virus calcivirin to produce mature capsid protein. {ECO:0000250}. |
Signal Peptide | |
Structure 3D | |
Cross Reference PDB | - |
Mapped Pubmed ID | - |
Motif | |
Gene Encoded By | |
Mass | 77,850 |
Kinetics | |
Metal Binding | |
Rhea ID | |
Cross Reference Brenda |