Detail Information for IndEnz0002003942
IED ID IndEnz0002003942
Enzyme Type ID protease003942
Protein Name Capsid protein
Coat protein
CP
VP1
Gene Name ORF2
Organism San Miguel sea lion virus serotype 1 (SMSV-1) (SMSV serotype 1)
Taxonomic Lineage Viruses Riboviria Orthornavirae Pisuviricota Pisoniviricetes Picornavirales Caliciviridae Vesivirus Vesicular exanthema of swine virus (VESV) San Miguel sea lion virus serotype 1 (SMSV-1) (SMSV serotype 1)
Enzyme Sequence MATTHTLLSFDDLEFLLHKKDLTDLYGERCGTLNLVINPYDLFLPDDLDDDWCDDPFNCCFSDVYTSIGTEYSYIDPPDLIYEEHCATNGHWPDGTPCEPILPPFVIEGTHHYYATKPGEAVSGILSKLGSAWDPDLQSTVDTKPDFVFRAESDGPGGADIVTEEQGTVVQQQPVPAQSALTTLAAASTGKTVDCEWTTFFSYHTAVNWSTTEAQGKILFSRALSPELNPYLRHISSLYSTWSGGIDVRFTVSGSGVFGGKLAALIVPPGIEPVESPTMLQYPHVLFDARQTEPVIFTIPDIRKTLYHSMDDTDTTRLVIMVYNELINPYEQSEPKSSCSITVETRPSSDFTFSLLKPPGSLLKHGSIPSDLIPRNSRHWMGNRWWSTIDGFVVQPRVFQSNRHFDFDSTTTGWSTPYYIPIEVTLEKLDRGGQYFKVTDTEKSLVPGLPDGWPDTTIPTAMTASNGNYDYTVAEYRITNNGTHFKGFYIMGNLTTKVKGSDNLGETQQTSRTLFASVGNYKDQNTINPTHKITSNSLVVYDANNVSAATAKTTTWHSTMSHLGYVLVDESPVGSDSTKVVRIATLPEAFTNGGNFPVFFTNKIQIGHFDRAHTKCFNSQVLMTSQKLAENHYTLPPDSLLVYRITDAASSWFDLGINHDGFSYVGISTIPELDFPLTFNLHGVQLAKVKLASKVKTSKTTI
Enzyme Length 702
Uniprot Accession Number P36284
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number
Enzyme Function FUNCTION: Capsid protein self assembles to form an icosahedral capsid with a T=3 symmetry, about 38 nm in diameter, and consisting of 180 capsid proteins. A smaller form of capsid with a diameter of 23 nm might be capsid proteins assembled as icosahedron with T=1 symmetry. The capsid encapsulate the genomic RNA and VP2 proteins. Attaches virion to target cells by binding to feline junctional adhesion molecule A (F11R) and/or to alpha-2,6-linked sialic acid. Once attached, the virion is endocytosed. Acidification of the endosome induces conformational change of capsid protein thereby injecting virus genomic RNA into host cytoplasm (By similarity). {ECO:0000250}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Chain (1); Propeptide (1); Site (1)
Keywords Capsid protein;Host cytoplasm;T=3 icosahedral capsid protein;Virion
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Virion. Host cytoplasm {ECO:0000250}.
Modified Residue
Post Translational Modification PTM: Cleaved by virus calcivirin to produce mature capsid protein. {ECO:0000250}.
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 77,850
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda