| IED ID | IndEnz0002003978 |
| Enzyme Type ID | protease003978 |
| Protein Name |
Hydrogenase 2 maturation protease EC 3.4.23.- |
| Gene Name | hybD b2993 JW2961 |
| Organism | Escherichia coli (strain K12) |
| Taxonomic Lineage | cellular organisms Bacteria Proteobacteria Gammaproteobacteria Enterobacterales Enterobacteriaceae Escherichia Escherichia coli Escherichia coli (strain K12) |
| Enzyme Sequence | MRILVLGVGNILLTDEAIGVRIVEALEQRYILPDYVEILDGGTAGMELLGDMANRDHLIIADAIVSKKNAPGTMMILRDEEVPALFTNKISPHQLGLADVLSALRFTGEFPKKLTLVGVIPESLEPHIGLTPTVEAMIEPALEQVLAALRESGVEAIPREAIHD |
| Enzyme Length | 164 |
| Uniprot Accession Number | P37182 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.23.- |
| Enzyme Function | FUNCTION: Protease involved in the C-terminal processing of HybC, the large subunit of hydrogenase 2. Specifically cleaves off a 15 amino acid peptide from the C-terminus of the precursor of HybC. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Beta strand (6); Chain (1); Helix (8); Metal binding (3); Sequence conflict (1); Turn (1) |
| Keywords | 3D-structure;Aspartyl protease;Hydrolase;Metal-binding;Nickel;Protease;Reference proteome |
| Interact With | |
| Induction | |
| Subcellular Location | |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | X-ray crystallography (1) |
| Cross Reference PDB | 1CFZ; |
| Mapped Pubmed ID | 16606699; 24561554; 7851435; 9738917; |
| Motif | |
| Gene Encoded By | |
| Mass | 17,751 |
| Kinetics | |
| Metal Binding | METAL 16; /note=Nickel; METAL 62; /note=Nickel; METAL 93; /note=Nickel |
| Rhea ID | |
| Cross Reference Brenda | 3.4.23.B20; |