| IED ID |
IndEnz0002003981 |
| Enzyme Type ID |
protease003981 |
| Protein Name |
Proteinase inhibitor
|
| Gene Name |
inh |
| Organism |
Dickeya chrysanthemi (Pectobacterium chrysanthemi) (Erwinia chrysanthemi) |
| Taxonomic Lineage |
cellular organisms
Bacteria
Proteobacteria
Gammaproteobacteria
Enterobacterales
Pectobacteriaceae
Dickeya
Dickeya chrysanthemi (Pectobacterium chrysanthemi) (Erwinia chrysanthemi)
|
| Enzyme Sequence |
MKQLIIATLLSALSGGCMASSLRLPSAAELSGQWVLSGAEQHCDIRLNTDVLDGTTWKLAGDTACLQKLLPEAPVGWRPTPDGLTLTQADGSAVAFFSRNRDRYEHKLVDGSVRTLKKKA |
| Enzyme Length |
120 |
| Uniprot Accession Number |
P18958 |
| Absorption |
|
| Active Site |
|
| Activity Regulation |
|
| Binding Site |
|
| Calcium Binding |
|
| catalytic Activity |
|
| DNA Binding |
|
| EC Number |
|
| Enzyme Function |
FUNCTION: Inhibitor of the extracellular proteases A, B, and C of E.chrysanthemi and the S.marcescens 50 kDa extracellular protease. It forms a non-covalent bond with the proteases and may prevent autocatalytic cleavage of the proteases zymogen in the periplasm. |
| Temperature Dependency |
|
| PH Dependency |
|
| Pathway |
|
| nucleotide Binding |
|
| Features |
Beta strand (9); Chain (1); Disulfide bond (1); Helix (2); Signal peptide (1) |
| Keywords |
3D-structure;Direct protein sequencing;Disulfide bond;Metalloenzyme inhibitor;Metalloprotease inhibitor;Periplasm;Protease inhibitor;Signal |
| Interact With |
|
| Induction |
|
| Subcellular Location |
SUBCELLULAR LOCATION: Periplasm. |
| Modified Residue |
|
| Post Translational Modification |
|
| Signal Peptide |
SIGNAL 1..19; /evidence=ECO:0000269|PubMed:2654540 |
| Structure 3D |
X-ray crystallography (1) |
| Cross Reference PDB |
1SMP;
|
| Mapped Pubmed ID |
- |
| Motif |
|
| Gene Encoded By |
|
| Mass |
12,909 |
| Kinetics |
|
| Metal Binding |
|
| Rhea ID |
|
| Cross Reference Brenda |
|