IED ID | IndEnz0002004092 |
Enzyme Type ID | protease004092 |
Protein Name |
Leucine aminopeptidase 1 EC 3.4.11.- Leucyl aminopeptidase 1 LAP1 |
Gene Name | LAP1 CMQ_3959 |
Organism | Grosmannia clavigera (strain kw1407 / UAMH 11150) (Blue stain fungus) (Graphiocladiella clavigera) |
Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta sordariomyceta Sordariomycetes Sordariomycetidae Ophiostomatales Ophiostomataceae Grosmannia Grosmannia clavigera Grosmannia clavigera (strain kw1407 / UAMH 11150) (Blue stain fungus) (Graphiocladiella clavigera) |
Enzyme Sequence | MKVSSAIALLLPVVAARFVDSAFEQDHVQLHPEQAAAEQFLIELSPGETRWVTEDEKWELRRNGQRFMDITDNRDLGLASAQSATTGPARVFPPNVTLDEEVFPLLANLSKGELQTHLEKLTSFHTRYYRSEHGRASSNWLLGQVKKTVGEAGGFKHGITVKPFKHPWGQNSVIARIPGQTNRTIVVGAHQDSINLFLPSVLSAPGADDDGSGTVTILEALRVLLQSEAVLAGKAANTIEFHWYSAEEGGLLGSQAIFNTYEKASRDVRAMLQQDMTGFVQRTLDAGEVESVGVIVDYVDPGLTAFIKKVITAYCDIPFIETKCGYACSDHASASKAGYPSAFVIESAFERSDDHIHTSDDLIKYLSFDHMLQHARLTLAFVYELAFADFDKLDKAAAVSVAPEMGDL |
Enzyme Length | 408 |
Uniprot Accession Number | F0X8C8 |
Absorption | |
Active Site | |
Activity Regulation | |
Binding Site | |
Calcium Binding | |
catalytic Activity | |
DNA Binding | |
EC Number | 3.4.11.- |
Enzyme Function | FUNCTION: Extracellular aminopeptidase that allows assimilation of proteinaceous substrates. {ECO:0000250}. |
Temperature Dependency | |
PH Dependency | |
Pathway | |
nucleotide Binding | |
Features | Chain (1); Disulfide bond (1); Glycosylation (3); Metal binding (6); Propeptide (1); Signal peptide (1) |
Keywords | Aminopeptidase;Disulfide bond;Glycoprotein;Hydrolase;Metal-binding;Protease;Reference proteome;Secreted;Signal;Zinc;Zymogen |
Interact With | |
Induction | |
Subcellular Location | SUBCELLULAR LOCATION: Secreted {ECO:0000250}. |
Modified Residue | |
Post Translational Modification | |
Signal Peptide | SIGNAL 1..16; /evidence=ECO:0000255 |
Structure 3D | |
Cross Reference PDB | - |
Mapped Pubmed ID | - |
Motif | |
Gene Encoded By | |
Mass | 44,744 |
Kinetics | |
Metal Binding | METAL 190; /note=Zinc 1; /evidence=ECO:0000250; METAL 209; /note=Zinc 1; /evidence=ECO:0000250; METAL 209; /note=Zinc 2; catalytic; /evidence=ECO:0000250; METAL 248; /note=Zinc 2; catalytic; /evidence=ECO:0000250; METAL 275; /note=Zinc 1; /evidence=ECO:0000250; METAL 357; /note=Zinc 2; catalytic; /evidence=ECO:0000250 |
Rhea ID | |
Cross Reference Brenda |