| IED ID | IndEnz0002004149 |
| Enzyme Type ID | protease004149 |
| Protein Name |
Kallikrein-15 EC 3.4.21.- |
| Gene Name | KLK15 |
| Organism | Saguinus oedipus (Cotton-top tamarin) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Craniata Vertebrata Gnathostomata (jawed vertebrates) Teleostomi Euteleostomi Sarcopterygii Dipnotetrapodomorpha Tetrapoda Amniota Mammalia Theria Eutheria Boreoeutheria Euarchontoglires Primates Haplorrhini Simiiformes Platyrrhini (New World monkeys) Cebidae Callitrichinae (marmosets and tamarins) Saguinus Saguinus oedipus (Cotton-top tamarin) |
| Enzyme Sequence | MWLLLPLSFLLTSTAQDGGKLLEGEECAPHSQPWQVALYERGRFNCGASLISPHWVLSAAHCQSRFMRVRLGEHNLRKRDGPEQLRTASRVIPHPRYEARSHRHDIMLLRLVQPARLTPQVRPVVLPTRCPHPGEACVVSGWGLVSHNEPGTTGRPQSQVSLPDTLHCANISIISDASCDKNYPGRLTNTMVCAGAEGRGAESCEGDSGGPLVCGGILQGIVSWGDVPCDNTTKPGVYTKVCRYVKWIRETMKRN |
| Enzyme Length | 255 |
| Uniprot Accession Number | Q7JIG6 |
| Absorption | |
| Active Site | ACT_SITE 61; /note=Charge relay system; /evidence=ECO:0000250; ACT_SITE 105; /note=Charge relay system; /evidence=ECO:0000250; ACT_SITE 208; /note=Charge relay system; /evidence=ECO:0000250 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.21.- |
| Enzyme Function | FUNCTION: Protease whose physiological substrate is not yet known. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (3); Chain (1); Disulfide bond (4); Glycosylation (2); Propeptide (1); Region (1); Signal peptide (1) |
| Keywords | Disulfide bond;Glycoprotein;Hydrolase;Protease;Secreted;Serine protease;Signal;Zymogen |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Secreted {ECO:0000305}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..15; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 28,078 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |