Detail Information for IndEnz0002004166
IED ID IndEnz0002004166
Enzyme Type ID protease004166
Protein Name Probable carboxypeptidase 2
EC 3.4.17.-
Carboxypeptidase M14B
Carboxypeptidase MCPB
Gene Name MCPB TRV_02159
Organism Trichophyton verrucosum (strain HKI 0517)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta Eurotiomycetes Eurotiomycetidae Onygenales Arthrodermataceae (dermatophytes) Trichophyton Trichophyton verrucosum (Cattle ringworm fungus) Trichophyton verrucosum (strain HKI 0517)
Enzyme Sequence MVAYHLLTLISLGLGSHCASALQYGYNQLSTHKDSAVVAGAFPAINGTHLQSPAFTSPGTVPRGFSDGTSGPTRDETMEGFMRRLARSNSWMAYHEADFKSEEGRKFPYMYLSASNSSVENPSSRKLRVWLQGGVHGNEPAGDQSMLALLGDLAANQKWAAKLLEKMDILVLPRYNPDGVFYFQRYLATNFDPNRDHIKLARQQTRDIKELFARFSPHIATDMHEFTAGRTFGPKRDIIYAADALFSAAKNLNIDEGIRQLSEELFAKRMGKDIEAAGLRWDPYITLGESSSSKLLLLEAGTDAKIGRNAMGLSQCVVFLCETRGIGIAGQHFERRTLSGLVMAKSILQTAVDNFDEVYNTIERGIRRFTNSRNDIVLSDKSPVMERTFGMLNITDASLFDYPIDFATTTPAEAVLTRSRPRAYLIPPSWPDIVKRLEVFGVKADKLPYSYVGPVEALNVTSVTFDKEYYEGVVTTTVETKLVERNIRLPAGSYLVKTNQKNAALAFVSLEVRTLYPF
Enzyme Length 518
Uniprot Accession Number D4D4Z1
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number 3.4.17.-
Enzyme Function FUNCTION: Extracellular metalloprotease that contributes to pathogenicity. {ECO:0000250}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Chain (1); Compositional bias (1); Erroneous gene model prediction (1); Glycosylation (4); Region (1); Signal peptide (1)
Keywords Carboxypeptidase;Glycoprotein;Hydrolase;Protease;Secreted;Signal;Virulence
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
Modified Residue
Post Translational Modification
Signal Peptide SIGNAL 1..21; /evidence=ECO:0000255
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 57,640
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda