| IED ID | IndEnz0002004300 |
| Enzyme Type ID | protease004300 |
| Protein Name |
Bradykinin-potentiating peptide T BPP-T Non-disulfide-bridged peptide 1.1 NDBP-1.1 Ts10 |
| Gene Name | |
| Organism | Tityus serrulatus (Brazilian scorpion) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Protostomia Ecdysozoa Panarthropoda Arthropoda Chelicerata Arachnida Scorpiones Buthida Buthoidea Buthidae Tityus Tityus serrulatus (Brazilian scorpion) |
| Enzyme Sequence | KKDGYPVEYDRAY |
| Enzyme Length | 13 |
| Uniprot Accession Number | Q9TWR4 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | |
| Enzyme Function | FUNCTION: Potentiates the contractile activity of bradykinin on the isolated guinea-pig ileum. Inhibits the hydrolysis of bradykinin by angiotensin-converting enzyme (ACE) and also inhibits the conversion of angiotensin I to angiotensin II by kininase II from guinea-pig ileum tissue. Also increases the depressor effect of bradykinin on arterial blood pressure in the anaesthetized rat. {ECO:0000269|PubMed:8212046}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Peptide (1) |
| Keywords | Direct protein sequencing;Hypotensive agent;Metalloenzyme inhibitor;Metalloprotease inhibitor;Protease inhibitor;Secreted |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:8212046}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 1,604 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |