| IED ID | IndEnz0002004309 |
| Enzyme Type ID | protease004309 |
| Protein Name |
Probable serine carboxypeptidase CPVL EC 3.4.16.- |
| Gene Name | CPVL |
| Organism | Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Craniata Vertebrata Gnathostomata (jawed vertebrates) Teleostomi Euteleostomi Sarcopterygii Dipnotetrapodomorpha Tetrapoda Amniota Mammalia Theria Eutheria Boreoeutheria Euarchontoglires Primates Haplorrhini Simiiformes Catarrhini Hominoidea (apes) Hominidae (great apes) Ponginae Pongo Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) |
| Enzyme Sequence | MVGTMWKVIVSLVLLMPGSCDGLFRSLYRSVSMPPKGDSGQPLFLTPYIEAGKIQKGRELSLVSPFLGLNMRSYAGFLTVNKTYNSNLFFWFFPAQIQPEDAPVVLWLQGGPGFSSMFGLFVEHGPYVVTSNMTLRDRDFPWTTTLSMLYIDNPVGTGFSFTDDTHGYAVNEDDVAQDLYSALIQFFQIFPEYKNNDFYVTGESYAGKYVPAIAHLIHSLNPVREVKINLKGIAIGDGYSDPESIIGGYAEFLYQIGLLDEKQKKYFQKQCHECIEHIRKQNWFQAFEILDKLLDGDLTSDPSYFQNVTGCSNYCNFLRCTEPEDQLYYAKFLSLPEVRQAIHVGNRTFNDGTTVEKYLREDTVQSVKPWLTEIMNNYKVLIYNGQLDIIVAAALTEHSLMGMDWKGSQEYKKAEKKVWKIFKSDSEVAGYVRQVGDFHQVIIRGGGHILPYIQPLRAFDMINRFIYGKGWDPYVG |
| Enzyme Length | 476 |
| Uniprot Accession Number | Q5RFE4 |
| Absorption | |
| Active Site | ACT_SITE 204; /evidence=ECO:0000255|PROSITE-ProRule:PRU10074; ACT_SITE 388; /evidence=ECO:0000255|PROSITE-ProRule:PRU10074; ACT_SITE 448; /evidence=ECO:0000255|PROSITE-ProRule:PRU10074 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.16.- |
| Enzyme Function | FUNCTION: May be involved in the digestion of phagocytosed particles in the lysosome, participation in an inflammatory protease cascade, and trimming of peptides for antigen presentation. {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (3); Chain (1); Glycosylation (4); Propeptide (1); Signal peptide (1) |
| Keywords | Carboxypeptidase;Glycoprotein;Hydrolase;Protease;Reference proteome;Signal;Zymogen |
| Interact With | |
| Induction | |
| Subcellular Location | |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..22; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 54,254 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |