| IED ID | IndEnz0002004311 |
| Enzyme Type ID | protease004311 |
| Protein Name |
Collagen alpha-1 XXIII chain |
| Gene Name | COL23A1 |
| Organism | Homo sapiens (Human) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Deuterostomia Chordata Craniata Vertebrata Gnathostomata (jawed vertebrates) Teleostomi Euteleostomi Sarcopterygii Dipnotetrapodomorpha Tetrapoda Amniota Mammalia Theria Eutheria Boreoeutheria Euarchontoglires Primates Haplorrhini Simiiformes Catarrhini Hominoidea (apes) Hominidae (great apes) Homininae Homo Homo sapiens (Human) |
| Enzyme Sequence | MGPGERAGGGGDAGKGNAAGGGGGGRSATTAGSRAVSALCLLLSVGSAAACLLLGVQAAALQGRVAALEEERELLRRAGPPGALDAWAEPHLERLLREKLDGLAKIRTAREAPSECVCPPGPPGRRGKPGRRGDPGPPGQSGRDGYPGPLGLDGKPGLPGPKGEKGAPGDFGPRGDQGQDGAAGPPGPPGPPGARGPPGDTGKDGPRGAQGPAGPKGEPGQDGEMGPKGPPGPKGEPGVPGKKGDDGTPSQPGPPGPKGEPGSMGPRGENGVDGAPGPKGEPGHRGTDGAAGPRGAPGLKGEQGDTVVIDYDGRILDALKGPPGPQGPPGPPGIPGAKGELGLPGAPGIDGEKGPKGQKGDPGEPGPAGLKGEAGEMGLSGLPGADGLKGEKGESASDSLQESLAQLIVEPGPPGPPGPPGPMGLQGIQGPKGLDGAKGEKGASGERGPSGLPGPVGPPGLIGLPGTKGEKGRPGEPGLDGFPGPRGEKGDRSERGEKGERGVPGRKGVKGQKGEPGPPGLDQPCPVGPDGLPVPGCWHK |
| Enzyme Length | 540 |
| Uniprot Accession Number | Q86Y22 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | |
| Enzyme Function | |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Alternative sequence (5); Chain (1); Compositional bias (2); Domain (5); Natural variant (1); Region (3); Topological domain (2); Transmembrane (1) |
| Keywords | Alternative splicing;Cell membrane;Collagen;Membrane;Reference proteome;Repeat;Signal-anchor;Transmembrane;Transmembrane helix |
| Interact With | Q96B26 |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Cell membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}; Extracellular side {ECO:0000250}. |
| Modified Residue | |
| Post Translational Modification | PTM: Undergoes proteolytic cleavage by furin protease to yield a 60 kDa soluble form that forms a homotrimer and exhibits a low affinity interaction with heparin. {ECO:0000250}. |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | 10934207; 12475640; 1323838; 14500733; 15044469; 15231747; 1577494; 16591531; 16728390; 171650; 17627939; 18487197; 19075007; 19693541; 19724895; 19851296; 20198315; 20379614; 20447926; 20470363; 21652699; 21878990; 21967573; 25416956; 2543975; 3173483; 6809411; 710450; 9054364; 9545296; 9560306; 9582318; |
| Motif | |
| Gene Encoded By | |
| Mass | 51,944 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |