| IED ID | IndEnz0002004345 |
| Enzyme Type ID | protease004345 |
| Protein Name |
ATP-dependent zinc metalloprotease FTSH, chloroplastic EC 3.4.24.- |
| Gene Name | FTSH |
| Organism | Medicago sativa (Alfalfa) |
| Taxonomic Lineage | cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae eudicotyledons Gunneridae Pentapetalae rosids fabids Fabales Fabaceae Papilionoideae 50 kb inversion clade NPAAA clade Hologalegina IRL clade Trifolieae Medicago (medics) Medicago sativa (Alfalfa) |
| Enzyme Sequence | MAFSTSSLLSTNFLGARNIPTPKTTKPSISLPLFFKTKFFNSQNDNNNNNSEPIKSAAVSALILSSMFTPAALAADNLPPPPPPVLEAQPNQLNPANSTSPFSQNISLTAPKPQAQSSTDLPDGSQWRYSEFLNAVKKGKVERVRFSKDGSVLQLTAVDGRRANVIVPNDPDLIDILAMNGVDISVSEGEQGNGLFSFVGSLLLPFLAFAGLFLIFRRGQGGPGGPGGLGGPMDFGRSKSKFQEVPETGVTFADVAGADQAKLELQEVVDFLKNPDKYTALGAKIPKGCLLVGPPGTGKTLLARAVAGEAGTPFFSCAASEFVELFVGVGASRVRDLFEKAKSKAPCIVFIDEIDAVGRQRGAGLGGGNDEREQTINQLLTEMDGFSGNSGVIVLAATNRPDVLDSALLRPGRFDRQVTVDRPDVAGRVKILQVHSRGKALAKDVDFDKIARRTPGFTGVDLQNLMNEAAILAARRDLKEISKDEIADALERIIAGPEKKNAVVSEEKKKLVAYHEAGHALVGALMPEYDPVAKISIIPRGQAGGLTFFAPSEERLESGLYSRSYLENQMAVALGGRVAEEVFGQDNVTTGASNDFMQVSRVARQMVERFGFSKKIGQVAIGGGGGNPFLGQQMSSQKDYSMATADIVDKEVRELVDKAYERATQIINTHIDILHKLAQLLIEKETVDGEEFMSLFIDGKAELYVS |
| Enzyme Length | 706 |
| Uniprot Accession Number | Q9BAE0 |
| Absorption | |
| Active Site | ACT_SITE 516; /evidence=ECO:0000250 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.24.- |
| Enzyme Function | FUNCTION: Seems to act as an ATP-dependent zinc metallopeptidase. {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | NP_BIND 293..300; /note=ATP; /evidence=ECO:0000255 |
| Features | Active site (1); Chain (1); Compositional bias (2); Metal binding (3); Nucleotide binding (1); Region (1); Transit peptide (1); Transmembrane (2) |
| Keywords | ATP-binding;Cell cycle;Cell division;Chloroplast;Hydrolase;Membrane;Metal-binding;Metalloprotease;Nucleotide-binding;Plastid;Protease;Transit peptide;Transmembrane;Transmembrane helix;Zinc |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Plastid, chloroplast membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 75,680 |
| Kinetics | |
| Metal Binding | METAL 515; /note=Zinc; catalytic; /evidence=ECO:0000250; METAL 519; /note=Zinc; catalytic; /evidence=ECO:0000250; METAL 595; /note=Zinc; catalytic; /evidence=ECO:0000250 |
| Rhea ID | |
| Cross Reference Brenda |