Detail Information for IndEnz0002004414
IED ID IndEnz0002004414
Enzyme Type ID protease004414
Protein Name Probable metalloendopeptidase G1-type
EC 3.4.24.-
Gene Name GP045L S045L
Organism Rabbit fibroma virus (strain Kasza) (RFV) (Shope fibroma virus (strain Kasza))
Taxonomic Lineage Viruses Varidnaviria Bamfordvirae Nucleocytoviricota Pokkesviricetes Chitovirales Poxviridae Chordopoxvirinae Leporipoxvirus Rabbit fibroma virus Rabbit fibroma virus (strain Kasza) (RFV) (Shope fibroma virus (strain Kasza))
Enzyme Sequence MIVFDNGVRVFINTSTNKDIYVGISGFGFEKDIGGILGTAHLLEHILISFDVSRFIANASTARSYMSFWCTSIRGRSTPVDAIRTLISWFFDRDGLKHYFPVSKIKYHIKELENEYYFRNEVFHCMDALTFLANGDLYNGGRLSMLDRLDDMPLILQDRMCAITGPNIVIFVRELNDVVLSLLVSTFGTLPSCPLTIPCTLPTPIGGKIIMMPSPFYTVMVRVQPSLYNILSILCLYEIYHLVDYETVNNKLYVTISFIHEHEYESFLHGSARLNFTIYKKIRLHYGDDFLMNMYLSFPCIRHDIFDYLTIINTNVSTMIPSLEQNIYQSIKTGDYIVVYPNFSNTMSNVADRQLHKTVVIDTNIVYVTKPTTVIDLMKKHTHNDMYIKYSDTEFIDYVQLALGLRRKIHKNVNGIHIRHQFSADDIKTILESETFMKYSKSKPAAMYQYLILSFFVSGNTIEDILQHRESVIKLCRTYKNKILLGKQTRYDIQTLSSFVCGIFKGPSITSEYLTDIMWKLKRKGLIYSLEFVELQKNMFYLFMFTIYPEDVTSYLTSRKLFTSRCVVVSKKCNVEDFSSMKKDIIIKLR
Enzyme Length 590
Uniprot Accession Number Q9Q926
Absorption
Active Site ACT_SITE 44; /evidence=ECO:0000255
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number 3.4.24.-
Enzyme Function FUNCTION: Seems to be involved in viral proteins maturation by cleavage at Ala-Gly-|-Xaa motifs. {ECO:0000250}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Active site (1); Chain (1); Metal binding (2)
Keywords Hydrolase;Metal-binding;Metalloprotease;Protease;Reference proteome;Zinc
Interact With
Induction
Subcellular Location
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 68,428
Kinetics
Metal Binding METAL 41; /note=Zinc; catalytic; /evidence=ECO:0000255; METAL 45; /note=Zinc; catalytic; /evidence=ECO:0000255
Rhea ID
Cross Reference Brenda