Detail Information for IndEnz0002004499
IED ID IndEnz0002004499
Enzyme Type ID protease004499
Protein Name Calpain-C
Calcium-activated neutral proteinase homolog C
CANP C
Gene Name CalpC CG3692
Organism Drosophila melanogaster (Fruit fly)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Protostomia Ecdysozoa Panarthropoda Arthropoda Mandibulata Pancrustacea Hexapoda Insecta Dicondylia Pterygota (winged insects) Neoptera Endopterygota Diptera Brachycera Muscomorpha Eremoneura Cyclorrhapha Schizophora Acalyptratae Ephydroidea Drosophilidae (pomace flies) Drosophilinae Drosophilini Drosophila (fruit flies) Sophophora melanogaster group melanogaster subgroup Drosophila melanogaster (Fruit fly)
Enzyme Sequence MASKYERILSDCRSKNVLWEDPDFPAVQSSVFYYQTPPFTFQWKRIMDLADSGSGAVAANSSAAPVFLNESAEFDVVPGKMGDRWLVSCLGLLSSLRNLFYRVVPADQTLASAHGVFRFRLWWCGEWVEVLVDDRLPTINGRLAFMQPQASNCFWAALLEKAIAKLHGSYEALKYGTRSDGLTDLLGGVVRQMPILSDNIRPQTLKELLTTTCIVTCLADKSATVAKKNLAERMPNGILVNVNYRLSSLDKVKTLMGDSVQLVCLKDTFSSKPFGEKTHFLGDWSPMSKTWERVSQVERARLIRQLGPGEFWLSFCDFVEIFSTMEVVYLDTETSNDEEMLKSRPLHWKMKMHQGQWKRGVTAGGCRNHESFHINPQLLISVQDEQDLVIALNQHTAVEPKVIGFTMYTWDGEYMLSECLQKDFFKNHVSYLNSDYGNTRHVSYHTHLEAGHYVLIPTTYEPAEEAHFTVRILGTGSFRLSCLETQTMILLDPFPALKSTDAERCGGPKVKSVCQYEPVYMQLADENKTINCFELHELLEACLPNDYIKGCANIDICRQVIALQDRSGSGRITFQQFKTFMVNLKSWQGVFKMYTKEKAGILRAERLRDALCDIGFQLSTDIMNCLIQRYIRKDGTLRLSDFVSAVIHLTTAFNQFHLKNYGQVNVIEVHLHDWIKSILSC
Enzyme Length 681
Uniprot Accession Number Q9VXH6
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding CA_BIND 565..576; /evidence=ECO:0000255|PROSITE-ProRule:PRU00448
catalytic Activity
DNA Binding
EC Number
Enzyme Function FUNCTION: Not known; does not seem to have protease activity.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Calcium binding (1); Chain (1); Domain (2); Region (3); Sequence conflict (6)
Keywords Calcium;Cytoplasm;Metal-binding;Reference proteome
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Cytoplasm {ECO:0000269|PubMed:12646209}.
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID 14605208; 15382138; 15451413; 18761085; 19442719; 20220848; 20371351; 21074052; 23071443; 25294943; 27172210; 29995573; 30705102; 32848200;
Motif
Gene Encoded By
Mass 77,448
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda 3.4.22.B38;