| IED ID | IndEnz0002004580 |
| Enzyme Type ID | protease004580 |
| Protein Name |
Probable thimet oligopeptidase EC 3.4.24.15 Zincin-like metalloproteases-like protein 1 |
| Gene Name | At1g67690 F12A21.16 |
| Organism | Arabidopsis thaliana (Mouse-ear cress) |
| Taxonomic Lineage | cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae eudicotyledons Gunneridae Pentapetalae rosids malvids Brassicales Brassicaceae Camelineae Arabidopsis Arabidopsis thaliana (Mouse-ear cress) |
| Enzyme Sequence | MTENEGNDKKIEGSNPKKKLNVVTFTGAAGLLGLAVSFAIFTFKSHKQKSKKKGLPGCDTVCVNLSAKEILDLAEEIIHKSTRVHDAVALVSLDKLSYENVVLPLAELEARQLSLIQCCVFPKMLSPHDNVRKASTEAEQKIDAHILSCRKREDVYRIIKIYAAKGESISPEAKCYLQCLVRDFEDNGLNLTAIKREEVERLKYEIDELSLRYIQNLNEDSSCLFFTEDELAGLPLEFLQNLEKTQNKEFKLTLESRHVAAILELCKIAKTRKTVAMAYGKRCGDTNIPVLQRLVQSRHRLACVCGYAHFADYALDRRMSKTSMRVIRFLEDISSSLTDLAIREFSILEDLKRKEEGEIPFGVEDLLYYIKRVEELQFDLDFGDIRQYFPVNLVLSGIFKICQDLFGIKFEEVTEVDVWYHDIRAFAVFDSGSGKLLGYFYLDMFTREGKCNHSCVVALQNNALFSNGACQIPVALLIAQFAKDGSGEAVPLGFSDVVNLFHEFGHVVQHICNRASFARFSGLRVDPDFREIPSQLLENWCYESFTLKLISGYRQDITKPLVDEVCKTLKRWRYSFSALKSLQEILYCLFDQIIYSDDDADLLQLIRSLHPKVMIGLPVVEGTNPASCFPRAVIGSEATCYSRLWSEVYAADIFASKFGDGHPNLYAGLQFRDKVLAPGGGKEPMELLTNFLGREPSTQAFIASRTNYSL |
| Enzyme Length | 710 |
| Uniprot Accession Number | F4HTQ1 |
| Absorption | |
| Active Site | ACT_SITE 503; /evidence=ECO:0000250 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=Preferential cleavage of bonds with hydrophobic residues at P1, P2 and P3' and a small residue at P1' in substrates of 5 to 15 residues.; EC=3.4.24.15; |
| DNA Binding | |
| EC Number | 3.4.24.15 |
| Enzyme Function | FUNCTION: Involved in cytoplasmic peptide degradation. {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (1); Chain (1); Erroneous gene model prediction (1); Metal binding (2) |
| Keywords | Cytoplasm;Hydrolase;Metal-binding;Metalloprotease;Protease;Reference proteome;Zinc |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | 12185496; 27100569; |
| Motif | |
| Gene Encoded By | |
| Mass | 80,291 |
| Kinetics | |
| Metal Binding | METAL 502; /note=Zinc; catalytic; /evidence=ECO:0000250; METAL 506; /note=Zinc; catalytic; /evidence=ECO:0000250 |
| Rhea ID | |
| Cross Reference Brenda |