| IED ID | IndEnz0002004583 |
| Enzyme Type ID | protease004583 |
| Protein Name |
Mitochondrial-processing peptidase subunit alpha-2 Alpha-MPP 2 Ddalpha-MPP 2 Inactive zinc metalloprotease alpha-2 |
| Gene Name | mppA2 pmpca DDB_G0290997 |
| Organism | Dictyostelium discoideum (Slime mold) |
| Taxonomic Lineage | cellular organisms Eukaryota Amoebozoa Evosea Eumycetozoa Dictyostelia (dictyostelid cellular slime molds) Dictyosteliales Dictyosteliaceae Dictyostelium Dictyostelium discoideum (Slime mold) |
| Enzyme Sequence | MIGRFIARNYTTSIFQESKRIVESTTLSNGLKVVSLVGGYTGPAVSLGLYIKTGSRNETQETAGLNQVLKGLAFESNTNKLGIEVQRDIEVSGSTAFAQASRDNLLIALQTLPNRSLQMLNNLANITKPTLPYHEVRDVTEIIVKESEAYNHDSYSSIFESVHQTAFRGKTLGRPLVAPICNLGNITKDAVTNWVNSTYKPSNMILVGVGLSHNELIEEAEKVTFGNDESSTSISNETAQYIGGESLKYSSGNSKVVLAFEGTAQSNIKDVAAFSVLQSILGNGCPKTAPGHGRTSRLFSLTKNNSNIVNSEAFNLTYGDSGLFGVVAEVEGATVGKTVSLITSEIVAASKTAGQELERAKAVTKSSVLEQAESRTSALEFIGKQAIYTDKVLTPAEFAEEISKVTSEDIKRVAKKMTSKKPTLVVVGDVSDAPTIESVQSQLKL |
| Enzyme Length | 445 |
| Uniprot Accession Number | Q54F93 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | |
| Enzyme Function | FUNCTION: Substrate recognition and binding subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins. {ECO:0000250|UniProtKB:Q86A84}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Transit peptide (1) |
| Keywords | Mitochondrion;Reference proteome;Transit peptide |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Mitochondrion matrix {ECO:0000250|UniProtKB:Q86A84}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | 19482547; 22120990; |
| Motif | |
| Gene Encoded By | |
| Mass | 47,746 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |