| IED ID | IndEnz0002004607 |
| Enzyme Type ID | protease004607 |
| Protein Name |
Probable periplasmic serine endoprotease DegP-like EC 3.4.21.107 Protease Do |
| Gene Name | Mmwyl1_1102 |
| Organism | Marinomonas sp. (strain MWYL1) |
| Taxonomic Lineage | cellular organisms Bacteria Proteobacteria Gammaproteobacteria Oceanospirillales Oceanospirillaceae Marinomonas unclassified Marinomonas Marinomonas sp. (strain MWYL1) |
| Enzyme Sequence | MNRLLKQVCMVVVSSFMMASMLTHAASLPDFTELVEKASPAVVNISTEQTVTTKTANEGGQQLGPNSEELNEFFKHFFGQQPFGQQAPPQQGQRSSLGSGFIISHDGYVLTNNHVIDGADVIHVRLNDRREYVAKLVGTDPRTDLALLKIEADDLPIVKMGDSDKLKPGQWVLAIGSPFGFDYTVTAGIVSATGRSLPSDNYVPFIQTDVAINPGNSGGPLFNLDGEVVGINSQIYTRSGGFMGVSFAIPSKVAMSVVDQLKSDGKVSRAWLGVLIQDVNNELAESFGLDRSNGALISRVLPDSPAEKAGLKSGDIILEFNGQSIAHSGELPYIVGQMKADEKVDAKVYRDGKEQTISVTLEARPNDPKVVAQSQQDQNRLGMIVGEVPADMAKKFEIDNGVVIEQVLGGTAARNGLQQGDVITMLNGKRITSVAEFAKIAKDIPSGRSVPMRVIRQGYPMFIPFKIMD |
| Enzyme Length | 469 |
| Uniprot Accession Number | A6VUA4 |
| Absorption | |
| Active Site | ACT_SITE 114; /note=Charge relay system; /evidence=ECO:0000250; ACT_SITE 144; /note=Charge relay system; /evidence=ECO:0000255; ACT_SITE 217; /note=Charge relay system; /evidence=ECO:0000250 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | CATALYTIC ACTIVITY: Reaction=Acts on substrates that are at least partially unfolded. The cleavage site P1 residue is normally between a pair of hydrophobic residues, such as Val-|-Val.; EC=3.4.21.107; |
| DNA Binding | |
| EC Number | 3.4.21.107 |
| Enzyme Function | FUNCTION: Might be efficient in the degradation of transiently denatured and unfolded proteins which accumulate in the periplasm following stress conditions. {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (3); Chain (1); Domain (2); Region (2); Signal peptide (1) |
| Keywords | Hydrolase;Periplasm;Protease;Repeat;Serine protease;Signal;Stress response |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Periplasm {ECO:0000305}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..25; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 50,582 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |