| IED ID | IndEnz0002004683 |
| Enzyme Type ID | protease004683 |
| Protein Name |
Protein MGR2 Mitochondrial genome-required protein 2 |
| Gene Name | MGR2 YPL098C |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Saccharomycotina (true yeasts) Saccharomycetes Saccharomycetales Saccharomycetaceae Saccharomyces Saccharomyces cerevisiae (Baker's yeast) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
| Enzyme Sequence | MPPLPQNYAQQQPSNWDKFKMGLMMGTTVGVCTGILFGGFAIATQGPGPDGVVRTLGKYIAGSAGTFGLFMSIGSIIRSDSESSPMSHPNLNLQQQARLEMWKLRAKYGIRKD |
| Enzyme Length | 113 |
| Uniprot Accession Number | Q02889 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | |
| Enzyme Function | FUNCTION: Required for cell viability in cells lacking mitochondrial DNA. {ECO:0000269|PubMed:16267274}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Topological domain (3); Transmembrane (2) |
| Keywords | Membrane;Reference proteome;Transmembrane;Transmembrane helix |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | 11283351; 14690591; 19536198; 22613836; 22806564; 22808334; 24040173; 24287567; 24866464; 25008211; 25083920; 25124039; 25435547; 25454944; 25676309; 26714107; 26751567; 26950608; 27590886; 31764998; |
| Motif | |
| Gene Encoded By | |
| Mass | 12,252 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |