Detail Information for IndEnz0002004697
IED ID IndEnz0002004697
Enzyme Type ID protease004697
Protein Name Bradykinin-potentiating peptide S
BPP-S
Gene Name
Organism Lycosa erythrognatha (Wolf spider) (Scaptocosa raptoria)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Protostomia Ecdysozoa Panarthropoda Arthropoda Chelicerata Arachnida Araneae (spiders) Araneomorphae Entelegynae RTA clade Lycosoidea Lycosidae (wolf spiders) Lycosa Lycosa erythrognatha (Wolf spider) (Scaptocosa raptoria)
Enzyme Sequence QAPWPDTISPP
Enzyme Length 11
Uniprot Accession Number P0C7S8
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number
Enzyme Function FUNCTION: This peptide potentiates the effects of bradykinin on smooth muscle, and inhibits the angiotensin-converting enzyme (ACE) in vitro. {ECO:0000269|PubMed:8783454}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Modified residue (1); Peptide (1)
Keywords Direct protein sequencing;Hypotensive agent;Metalloenzyme inhibitor;Metalloprotease inhibitor;Protease inhibitor;Pyrrolidone carboxylic acid;Secreted
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:8783454}.
Modified Residue MOD_RES 1; /note=Pyrrolidone carboxylic acid; /evidence=ECO:0000269|PubMed:8783454
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 1,208
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda