| IED ID | IndEnz0002004712 |
| Enzyme Type ID | protease004712 |
| Protein Name |
Peptidoglycan DL-endopeptidase CwlO EC 3.4.-.- D-gamma-glutamyl-meso-diaminopimelyl DL-endopeptidase |
| Gene Name | cwlO BLi00347 BL01691 |
| Organism | Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / CCUG 7422 / NBRC 12200 / NCIMB 9375 / NCTC 10341 / NRRL NRS-1264 / Gibson 46) |
| Taxonomic Lineage | cellular organisms Bacteria Terrabacteria group Firmicutes Bacilli Bacillales Bacillaceae Bacillus Bacillus subtilis group Bacillus licheniformis Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / CCUG 7422 / NBRC 12200 / NCIMB 9375 / NCTC 10341 / NRRL NRS-1264 / Gibson 46) |
| Enzyme Sequence | MKKKVYTFGLASILGTASLFTPFMNNTASAETSQQKQEIQQKRSEVNSGIESKRKEIAKLQDEQKKLEGKIQELDKKALETSNKIEDKEKENKKTKKEVEALKKEIKETEKRIEERSKVIKNRVRSLQENGGSQNYLNVLLGAQSFGDFITRATAVSTIVDADKDLLDEQEKDKNKLEKAMSDLNTKLDEIQKTLADLKTLKSDLDKQLKEQANLSKQLQTKQAAAESELSDLKKEAGSLTKEEAALEQKLKEERAAAAAAAKAKEESATAEKSDSGSSSSSNSGSVSKSDGSSNSGSSSSKKSSSPSRNYSSGSVVSSNGNAIEAAISTGSSIVGRSPYKWGGGRSQADIDNRRFDCSSFVRWAYASAGVELGFGATTSTLVGKGRAVSASEMKRGDLVFFDTYKTNGHVGIYLGNGTFLNDNSSRGVSVDSMSNPYWKKAFNGVVRRVVE |
| Enzyme Length | 452 |
| Uniprot Accession Number | Q65NQ9 |
| Absorption | |
| Active Site | ACT_SITE 358; /note=Nucleophile; /evidence=ECO:0000255|PROSITE-ProRule:PRU01284; ACT_SITE 410; /note=Proton acceptor; /evidence=ECO:0000255|PROSITE-ProRule:PRU01284; ACT_SITE 422; /evidence=ECO:0000255|PROSITE-ProRule:PRU01284 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.-.- |
| Enzyme Function | FUNCTION: Shows a cell wall hydrolytic DL-endopeptidase activity. {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (3); Chain (1); Compositional bias (3); Domain (1); Region (2); Signal peptide (1) |
| Keywords | Cell wall biogenesis/degradation;Hydrolase;Protease;Reference proteome;Secreted;Signal;Thiol protease |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Secreted {ECO:0000250}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..30; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 49,109 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |