| IED ID | IndEnz0002004803 |
| Enzyme Type ID | protease004803 |
| Protein Name |
Carboxypeptidase Y inhibitor CPY inhibitor CDC25 suppressor 1 I C Ic Protein DKA1 Protein NSP1 |
| Gene Name | TFS1 DKA1 NSP1 YLR178C L9470.19 |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Saccharomycotina (true yeasts) Saccharomycetes Saccharomycetales Saccharomycetaceae Saccharomyces Saccharomyces cerevisiae (Baker's yeast) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
| Enzyme Sequence | MNQAIDFAQASIDSYKKHGILEDVIHDTSFQPSGILAVEYSSSAPVAMGNTLPTEKARSKPQFQFTFNKQMQKSVPQANAYVPQDDDLFTLVMTDPDAPSKTDHKWSEFCHLVECDLKLLNEATHETSGATEFFASEFNTKGSNTLIEYMGPAPPKGSGPHRYVFLLYKQPKGVDSSKFSKIKDRPNWGYGTPATGVGKWAKENNLQLVASNFFYAETK |
| Enzyme Length | 219 |
| Uniprot Accession Number | P14306 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | |
| Enzyme Function | FUNCTION: Specific and potent inhibitor of carboxypeptidase Y. {ECO:0000269|PubMed:9521655}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Beta strand (10); Chain (1); Helix (7); Modified residue (1); Sequence conflict (3); Turn (1) |
| Keywords | 3D-structure;Acetylation;Cytoplasm;Protease inhibitor;Reference proteome;Serine protease inhibitor |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Cytoplasm. |
| Modified Residue | MOD_RES 1; /note=N-acetylmethionine; /evidence=ECO:0000269|PubMed:12473200 |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | X-ray crystallography (1) |
| Cross Reference PDB | 1WPX; |
| Mapped Pubmed ID | 12791700; 15075275; 15229224; 15713484; 16429126; 16554755; 17076703; 17317927; 17945254; 18930818; 19536198; 19552705; 22365828; 22515269; 22842922; 23514415; 7641877; |
| Motif | |
| Gene Encoded By | |
| Mass | 24,357 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |