| IED ID |
IndEnz0002004819 |
| Enzyme Type ID |
protease004819 |
| Protein Name |
U-Kazal-Dg21.2
|
| Gene Name |
|
| Organism |
Dolopus genitalis (Giant Australian assassin fly) (Asilus genitalis) |
| Taxonomic Lineage |
cellular organisms
Eukaryota
Opisthokonta
Metazoa
Eumetazoa
Bilateria
Protostomia
Ecdysozoa
Panarthropoda
Arthropoda
Mandibulata
Pancrustacea
Hexapoda
Insecta
Dicondylia
Pterygota (winged insects)
Neoptera
Endopterygota
Diptera
Brachycera
Muscomorpha
Asiloidea
Asilidae (robber flies)
Asilinae
Dolopus
Dolopus genitalis (Giant Australian assassin fly) (Asilus genitalis)
|
| Enzyme Sequence |
MKYFLWSAVTIFAIVNVVGAKNSDFDPRCLRACTAIYRPVCGFDGKQYRIFASECVMAFENCNLLLKSQKAFQKTLMSFCQVEEDFDSDFCPEVCPLLYKPVCGSYGDIKKIFPNECELKRANCKFGEAWEKINMDICRNISFKSELIDPKKKCLKPCNLNWDPICAFDGEKYFTFGNRCDMEIQTCLRSEKNWTLIRKGEC |
| Enzyme Length |
202 |
| Uniprot Accession Number |
A0A3G5BID2 |
| Absorption |
|
| Active Site |
|
| Activity Regulation |
|
| Binding Site |
|
| Calcium Binding |
|
| catalytic Activity |
|
| DNA Binding |
|
| EC Number |
|
| Enzyme Function |
FUNCTION: May act as a serine protease inhibitor, since it possess the kazal serine protease inhibitor signature (Probable). The recombinant peptide does not produce toxic effects on insects (PubMed:31870846). {ECO:0000269|PubMed:31870846, ECO:0000305}. |
| Temperature Dependency |
|
| PH Dependency |
|
| Pathway |
|
| nucleotide Binding |
|
| Features |
Chain (1); Disulfide bond (8); Domain (3); Glycosylation (2); Propeptide (2); Signal peptide (1); Site (3) |
| Keywords |
Disulfide bond;Glycoprotein;Protease inhibitor;Repeat;Secreted;Serine protease inhibitor;Signal |
| Interact With |
|
| Induction |
|
| Subcellular Location |
SUBCELLULAR LOCATION: Secreted {ECO:0000269|PubMed:31870846}. |
| Modified Residue |
|
| Post Translational Modification |
|
| Signal Peptide |
SIGNAL 1..20; /evidence=ECO:0000255 |
| Structure 3D |
|
| Cross Reference PDB |
- |
| Mapped Pubmed ID |
- |
| Motif |
|
| Gene Encoded By |
|
| Mass |
23,371 |
| Kinetics |
|
| Metal Binding |
|
| Rhea ID |
|
| Cross Reference Brenda |
|