| IED ID | IndEnz0002004914 |
| Enzyme Type ID | protease004914 |
| Protein Name |
Alkaline protease EC 3.4.21.- |
| Gene Name | |
| Organism | Alkalihalobacillus alcalophilus (Bacillus alcalophilus) |
| Taxonomic Lineage | cellular organisms Bacteria Terrabacteria group Firmicutes Bacilli Bacillales Bacillaceae Alkalihalobacillus Alkalihalobacillus alcalophilus (Bacillus alcalophilus) |
| Enzyme Sequence | MKKPLGKIVASTALLISVAFSSSIASAAEEAKEKYLIGFNEQEAVSEFVEQVEANDEVAILSEEEEVEIELLHEFETIPVLSVELSPEDVDALELDPAISYIEEDAEVTTMAQSVPWGISRVQAPAAHNRGLTGSGVKVAVLDTGISTHPDLNIRGGASFVPGEPSTQDGNGHGTHVAGTIAALNNSIGVLGVAPNAELYAVKVLGASGSGSVSSIAQGLEWAGNNGMHVANLSLGSPSPSATLEQAVNSATSRGVLVVAASGNSGAGSISYPARYANAMAVGATDQNNNRASFSQYGAGLDIVAPGVNVQSTYPGSTYASLNGTSMATPHVAGAAALVKQKNPSWSNVQIRNHLKNTATSLGSTNLYGSGLVNAEAATR |
| Enzyme Length | 380 |
| Uniprot Accession Number | P27693 |
| Absorption | |
| Active Site | ACT_SITE 143; /note=Charge relay system; /evidence=ECO:0000255|PROSITE-ProRule:PRU01240; ACT_SITE 173; /note=Charge relay system; /evidence=ECO:0000255|PROSITE-ProRule:PRU01240; ACT_SITE 326; /note=Charge relay system; /evidence=ECO:0000255|PROSITE-ProRule:PRU01240 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.21.- |
| Enzyme Function | |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (3); Beta strand (11); Chain (1); Domain (2); Helix (8); Metal binding (9); Propeptide (1); Signal peptide (1); Turn (4) |
| Keywords | 3D-structure;Calcium;Hydrolase;Metal-binding;Protease;Secreted;Serine protease;Signal;Zymogen |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Secreted. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..27; /evidence=ECO:0000255 |
| Structure 3D | NMR spectroscopy (1) |
| Cross Reference PDB | 1AH2; |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 38,853 |
| Kinetics | |
| Metal Binding | METAL 113; /note=Calcium 1; METAL 151; /note=Calcium 1; METAL 184; /note=Calcium 1; via carbonyl oxygen; METAL 186; /note=Calcium 1; METAL 188; /note=Calcium 1; via carbonyl oxygen; METAL 190; /note=Calcium 1; via carbonyl oxygen; METAL 274; /note=Calcium 2; via carbonyl oxygen; METAL 276; /note=Calcium 2; via carbonyl oxygen; METAL 279; /note=Calcium 2; via carbonyl oxygen |
| Rhea ID | |
| Cross Reference Brenda |