Detail Information for IndEnz0002005017
IED ID IndEnz0002005017
Enzyme Type ID protease005017
Protein Name Inducible serine protease inhibitor 2
ISPI-2
Fragment
Gene Name
Organism Galleria mellonella (Greater wax moth)
Taxonomic Lineage cellular organisms Eukaryota Opisthokonta Metazoa Eumetazoa Bilateria Protostomia Ecdysozoa Panarthropoda Arthropoda Mandibulata Pancrustacea Hexapoda Insecta Dicondylia Pterygota (winged insects) Neoptera Endopterygota Amphiesmenoptera Lepidoptera (butterflies and moths) Glossata Neolepidoptera Heteroneura Ditrysia Obtectomera Pyraloidea Pyralidae (snout moths) Galleriinae Galleria Galleria mellonella (Greater wax moth)
Enzyme Sequence LDPKCTLPLETGICRAELHRFGYDTKLKECTQFVYGGCHHNENNFKKLEVCR
Enzyme Length 52
Uniprot Accession Number P81906
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number
Enzyme Function FUNCTION: Inhibits trypsin and the toxin protease PR2 of M.anisopliae. Does not inhibit chymotrypsin, subtilisin Carlsberg, proteinase K, porcine pancreatic elastase and the toxin protease PR1 of M.anisopliae.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Chain (1); Disulfide bond (2); Domain (1); Non-terminal residue (1); Site (1)
Keywords Direct protein sequencing;Disulfide bond;Protease inhibitor;Reference proteome;Serine protease inhibitor
Interact With
Induction INDUCTION: By infection.
Subcellular Location
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 6,057
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda