| IED ID | IndEnz0002005084 |
| Enzyme Type ID | protease005084 |
| Protein Name |
Antifungal protein J AFP-J Fragment |
| Gene Name | |
| Organism | Solanum tuberosum (Potato) |
| Taxonomic Lineage | cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae eudicotyledons Gunneridae Pentapetalae asterids lamiids Solanales Solanaceae Solanoideae Solaneae Solanum Solanum tuberosum (Potato) |
| Enzyme Sequence | LPSDATLVLDQTGKELDARL |
| Enzyme Length | 20 |
| Uniprot Accession Number | P84794 |
| Absorption | |
| Active Site | |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | |
| Enzyme Function | FUNCTION: Inhibitor of serine proteases chymotrypsin, pepsin and trypsin. Has strong antifungal activity against the human pathogenic fungi C.albicans TIMM 1768, S.cerevisiae KCTC 7296 and T.beigelli KCTC 7707, but lacks antifungal activity against the plant pathogenic fungi C.gloeosporioides KACC 40003, C.coccodes KACC 40803 and D.bryoniae KACC 40669. Lacks hemolytic activity against human erythrocytes. {ECO:0000269|PubMed:16076139}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Chain (1); Non-terminal residue (1) |
| Keywords | Antimicrobial;Direct protein sequencing;Fungicide;Protease inhibitor;Reference proteome;Serine protease inhibitor;Vacuole |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Vacuole {ECO:0000250|UniProtKB:P30941}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 2,155 |
| Kinetics | |
| Metal Binding | |
| Rhea ID | |
| Cross Reference Brenda |