| IED ID | IndEnz0002005097 |
| Enzyme Type ID | protease005097 |
| Protein Name |
Disintegrin and metalloproteinase domain-containing protein B ADAM B EC 3.4.24.- |
| Gene Name | ADM-B MCYG_06406 |
| Organism | Arthroderma otae (strain ATCC MYA-4605 / CBS 113480) (Microsporum canis) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta Eurotiomycetes Eurotiomycetidae Onygenales Arthrodermataceae (dermatophytes) Microsporum Arthroderma otae (Microsporum canis) Arthroderma otae (strain ATCC MYA-4605 / CBS 113480) (Microsporum canis) |
| Enzyme Sequence | MKALSCLLAVIATAGSLFQHVDARSHARDRLNNISRVERPVIHTPSHRVHAHSHFDLTFDLYPRSSRIKLQLEPNHDVLSHDARVAFLDGEGNVDRMERIERRDHRVFKGWAWVQRKSGSWERVGWARVMMQRDGEDPLFEGVFTVMHDHHQIIPKTKYVHKRHPHDPPLDATPGEYMLLFRGSDIRTQTHDTVERSITSSPSCDADTLAYGTQSDFMFPPLPQENNTNLWGSLMTSIGRRQNSDTVGTVPGSQNLRDTIGNTDGCPNTRRVALIGVVADCTYTSTFASEMDAKTDIISVVNAASVVYEHTFNISLTLGEVNILPKNCPATASSATPFNQMCGERVGDESFTLADRLNTFSAWRGKKSDDFAFWTLMTDCTTENQVGLAWAAQLCVKGVQGDSNTRNASSQAVSGANVVSKTDNTWQVFAHEAGHIFGAVHDCDSALCQDPSNPDNSRCCPSTATTCDAGGKFMMNPTSGSQITAFSPCSVGQICSRMAKHSILTNCLTTNRGVDTISGQQCGNGIVEDGEDCDCGGDESCKGNKCCDPKTCKYTSGSQCDDANEECCRDCKFASSSTICRLSSGPCDPEEKCTGNSGDCPRDTHSKNGETCGTNLQCASGQCTSRDLQCQMHLGSQVAGSRTVAFDSYGCQVACKDPYRPDVRYEGSLTFLDGTPCGGGGTCENGQCTGSTFGNEVSDWVSRHKPIVIGVAVGVGCLLLLAILSCICGRSKKRRPRNRKMAPINMRPMPPVYNGWTGPPPNAESPGGHPQYNHVPPPINAPPPAYPGRMPSTRYA |
| Enzyme Length | 796 |
| Uniprot Accession Number | C5FUK3 |
| Absorption | |
| Active Site | ACT_SITE 432; /evidence=ECO:0000255|PROSITE-ProRule:PRU00276 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.24.- |
| Enzyme Function | FUNCTION: Probable zinc protease. {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (1); Chain (1); Compositional bias (1); Disulfide bond (3); Domain (2); Glycosylation (4); Metal binding (3); Region (1); Signal peptide (1); Topological domain (2); Transmembrane (1) |
| Keywords | Disulfide bond;Glycoprotein;Hydrolase;Membrane;Metal-binding;Metalloprotease;Protease;Reference proteome;Signal;Transmembrane;Transmembrane helix;Zinc |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | SIGNAL 1..23; /evidence=ECO:0000255 |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 86,526 |
| Kinetics | |
| Metal Binding | METAL 431; /note=Zinc; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU00276; METAL 435; /note=Zinc; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU00276; METAL 441; /note=Zinc; catalytic; /evidence=ECO:0000255|PROSITE-ProRule:PRU00276 |
| Rhea ID | |
| Cross Reference Brenda |