| IED ID | IndEnz0002005376 |
| Enzyme Type ID | protease005376 |
| Protein Name |
Mitochondrial presequence protease EC 3.4.24.- |
| Gene Name | cym1 AO090023000781 |
| Organism | Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold) |
| Taxonomic Lineage | cellular organisms Eukaryota Opisthokonta Fungi Dikarya Ascomycota saccharomyceta Pezizomycotina leotiomyceta Eurotiomycetes Eurotiomycetidae Eurotiales (green and blue molds) Aspergillaceae Aspergillus Aspergillus subgen. Circumdati Aspergillus oryzae (Yellow koji mold) Aspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold) |
| Enzyme Sequence | MAADDIVGCYQVDKARRSLTNVESYPKVGEQLHGFTVQEKKHVPELHLTAVRLKHDKTDADYLHVAREDKNNVFGVGFKTNPPDATGVPHILEHTTLCGSEKYPVRDPFFKMLPRSLSNFMNAFTSADHTTYPFATTNQQDFQNLLSVYLDATLHPLLKEEDFRQEGWRLGPEDPRASDALDGKPEDVLFKGVVYNEMKGQISDANYLYYIKYRESIFPALNNSGGDPQYITDLTHKQLVEFSKRNYHPSNAKFLTYGDMPLSTHLKQIGDVLDGFGKGEADTSVKLPIDLSRGPSNVTVPGPIDTFADADKQYKTSTSWYLGDTSEVVETFSAGILSSLLLDGYGSPMYRALIESGLGSSFTPNTGLDTSGRVPVLSVGLTGVSEEDAPKVKEAIQKVYQDSLSAGFSDEKVQGFLHQLELALRHKTANFGIGVMEKTISSWFNGVDPMKELAWNDVINEFKRRYQQGGYLESLMQKYLMNDRCLTFTMVGTPTFHQELDQQEMVRKEKKLSQLVEQHGSMEKAISSLREQELQLLKTQEEAQHADLGCLPSLRVEDISREKERKPVRESKVDDVDVVWREAPTNGLTYFQALNAFEDLPDDLRLLMPLFNDSVMRLGTANKTMEQWEDLIKLKTGGVSSSAFHTSSPTELGKFNEGLQFSGFALDKNIPDMLEILTTLITETDFTSPYAPAMIQELLRLTTNGALDSVAASGHRFALNAAAAGLSRSFWVQEQQSGLAQLQATANLLRDAETSPERLAELIEKLRLIQSFAISKSSSLRVRMVCEPSSAHQNEVVLQKWLAGLPQIRSPTSVDARSMQQVSSKAFYDMPYKVYYSGLAMQTVPFVHKSSAPLSVLSQLLTHNYLHPEIREKGGAYGAAASNGPVKGIFALTSYRDPNPLNTLKVFQNSGIFARDRSWSERELNEAKLGIFQGLDAPVSVDEEGSRYFMSGVTHEMDQRWREQLLDVTARDVNEVAQTFLVDGPRQSVCLLGEKKDWAEDWDVRKLSMNAGEAEAYPEDASTTA |
| Enzyme Length | 1025 |
| Uniprot Accession Number | Q2UGN1 |
| Absorption | |
| Active Site | ACT_SITE 93; /note=Proton acceptor; /evidence=ECO:0000250 |
| Activity Regulation | |
| Binding Site | |
| Calcium Binding | |
| catalytic Activity | |
| DNA Binding | |
| EC Number | 3.4.24.- |
| Enzyme Function | FUNCTION: ATP-independent protease that degrades mitochondrial transit peptides after their cleavage. Also degrades other unstructured peptides (By similarity). {ECO:0000250}. |
| Temperature Dependency | |
| PH Dependency | |
| Pathway | |
| nucleotide Binding | |
| Features | Active site (1); Chain (1); Metal binding (3) |
| Keywords | Hydrolase;Metal-binding;Metalloprotease;Mitochondrion;Protease;Reference proteome;Zinc |
| Interact With | |
| Induction | |
| Subcellular Location | SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250}. |
| Modified Residue | |
| Post Translational Modification | |
| Signal Peptide | |
| Structure 3D | |
| Cross Reference PDB | - |
| Mapped Pubmed ID | - |
| Motif | |
| Gene Encoded By | |
| Mass | 114,432 |
| Kinetics | |
| Metal Binding | METAL 90; /note=Zinc; catalytic; /evidence=ECO:0000250; METAL 94; /note=Zinc; catalytic; /evidence=ECO:0000250; METAL 197; /note=Zinc; catalytic; /evidence=ECO:0000250 |
| Rhea ID | |
| Cross Reference Brenda |