Detail Information for IndEnz0002005389
IED ID IndEnz0002005389
Enzyme Type ID protease005389
Protein Name COP9 signalosome complex subunit 6b
Signalosome subunit 6b
Fragments
Gene Name CSN6B
Organism Brassica oleracea (Wild cabbage)
Taxonomic Lineage cellular organisms Eukaryota Viridiplantae Streptophyta Streptophytina Embryophyta Tracheophyta Euphyllophyta Spermatophyta Magnoliopsida Mesangiospermae eudicotyledons Gunneridae Pentapetalae rosids malvids Brassicales Brassicaceae Brassiceae Brassica Brassica oleracea (Wild cabbage)
Enzyme Sequence KLHPLVMLNISDHLTKALMDINESPVYVLLNPTINHAQKKMLNSRIRVLHQYLGSMQK
Enzyme Length 58
Uniprot Accession Number P68357
Absorption
Active Site
Activity Regulation
Binding Site
Calcium Binding
catalytic Activity
DNA Binding
EC Number
Enzyme Function FUNCTION: Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes such as photomorphogenesis and auxin and jasmonate responses. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF. It is involved in repression of photomorphogenesis in darkness by regulating the activity of COP1-containing Ubl ligase complexes (By similarity). {ECO:0000250}.
Temperature Dependency
PH Dependency
Pathway
nucleotide Binding
Features Chain (1); Non-adjacent residues (2); Non-terminal residue (2)
Keywords Cytoplasm;Developmental protein;Direct protein sequencing;Nucleus;Phytochrome signaling pathway;Signalosome
Interact With
Induction
Subcellular Location SUBCELLULAR LOCATION: Cytoplasm. Nucleus.
Modified Residue
Post Translational Modification
Signal Peptide
Structure 3D
Cross Reference PDB -
Mapped Pubmed ID -
Motif
Gene Encoded By
Mass 6,707
Kinetics
Metal Binding
Rhea ID
Cross Reference Brenda